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Table 2 Odd’s ratio (OR) and confidence interval (CI) for the association between dietary quality indices and MC4R rs17782313 genotypes

From: Melanocortin-4 receptor (MC4R) rs17782313 polymorphism interacts with Dietary Approach to Stop Hypertension (DASH) and Mediterranean Dietary Score (MDS) to affect hypothalamic hormones and cardio-metabolic risk factors among obese individuals

 

Women

Men

 

TT

TC

CC

TT

TC

CC

MDS (total score)

Crude

1 (Ref.)

1.04 (0.75–1.44)

1.10 (0.75–1.62)

1 (Ref.)

1.40 (0.89–2.18)

1.68 (0.94–2.95)

Model 1*

1 (Ref.)

1.08 (0.77–1.52)

1.12 (0.73–1.72)

1 (Ref.)

1.50 (0.94–2.40)

1.66 (0.92–3.02)

Model 2**

1 (Ref.)

1.08 (0.77–1.52)

1.11 (0.71–1.71)

1 (Ref.)

1.48 (0.92–2.37)

1.76 (0.96–3.22)

DASH score (total score)

Crude

1 (Ref.)

0.94 (0.83–1.06)

0.87 (0.75–1.01)

1 (Ref.)

1.09 (0.95–1.24)

1.13 (0.95–1.35)

Model 1

1 (Ref.)

0.94 (0.82–1.07)

0.86 (0.73–1.01)

1 (Ref.)

1.16 (0.99–1.35)

1.19 (0.97–1.46)

Model 2

1 (Ref.)

0.94 (0.82–1.06)

0.83 (0.70–0.99)

1 (Ref.)

1.17 (1.00–1.36)

1.18 (0.95–1.45)

  1. The multivariate multinomial logistic regression was used for estimation of ORs and confidence interval (CI)
  2. *Adjusted for age, physical activity, and socio-economic status
  3. **Additionally adjusted for waist circumference. Indicates statistically significant values as p < 0.05