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Table 2 Odd’s ratio (OR) and confidence interval (CI) for the association between dietary quality indices and MC4R rs17782313 genotypes

From: Melanocortin-4 receptor (MC4R) rs17782313 polymorphism interacts with Dietary Approach to Stop Hypertension (DASH) and Mediterranean Dietary Score (MDS) to affect hypothalamic hormones and cardio-metabolic risk factors among obese individuals

  Women Men
  TT TC CC TT TC CC
MDS (total score)
Crude 1 (Ref.) 1.04 (0.75–1.44) 1.10 (0.75–1.62) 1 (Ref.) 1.40 (0.89–2.18) 1.68 (0.94–2.95)
Model 1* 1 (Ref.) 1.08 (0.77–1.52) 1.12 (0.73–1.72) 1 (Ref.) 1.50 (0.94–2.40) 1.66 (0.92–3.02)
Model 2** 1 (Ref.) 1.08 (0.77–1.52) 1.11 (0.71–1.71) 1 (Ref.) 1.48 (0.92–2.37) 1.76 (0.96–3.22)
DASH score (total score)
Crude 1 (Ref.) 0.94 (0.83–1.06) 0.87 (0.75–1.01) 1 (Ref.) 1.09 (0.95–1.24) 1.13 (0.95–1.35)
Model 1 1 (Ref.) 0.94 (0.82–1.07) 0.86 (0.73–1.01) 1 (Ref.) 1.16 (0.99–1.35) 1.19 (0.97–1.46)
Model 2 1 (Ref.) 0.94 (0.82–1.06) 0.83 (0.70–0.99) 1 (Ref.) 1.17 (1.00–1.36) 1.18 (0.95–1.45)
  1. The multivariate multinomial logistic regression was used for estimation of ORs and confidence interval (CI)
  2. *Adjusted for age, physical activity, and socio-economic status
  3. **Additionally adjusted for waist circumference. Indicates statistically significant values as p < 0.05
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Genes & Nutrition

ISSN: 1865-3499

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