Table 2 The serum parameters of sham-operated (control) and castrated-male rats fed either normal diet or high-fat diet at 8-h fasted state

Testosterone, pg/mL

8.30 ± 1.04^a

2.39 ± 0.13^b

11.0 ± 1.57^a

1.73 ± 0.39^b

< 0.001

NS

NS

Free fatty acid, μEq/L

439 ± 43.3^b

649 ± 41.3^a

418 ± 31.7^b

533 ± 25.4^b

< 0.001

NS

NS

Insulin, ng/mL

4.27 ± 0.38^a

4.25 ± 0.23^a

2.43 ± 0.34^b

1.38 ± 0.31^b

NS

< 0.001

NS

Total cholesterol, mg/dL

78.5 ± 2.87^b

105 ± 3.74^a

97.5 ± 4.50^a

112 ± 6.17^a

< 0.001

0.02

NS

LDL cholesterol, mg/dL

7.1 ± 0.56^b

10.2 ± 1.57^a

15.7 ± 1.30^a

13.2 ± 0.69^a

NS

< 0.001

0.04

HDL cholesterol, mg/dL

69.4 ± 2.76^b

95.1 ± 4.59^a

83.3 ± 5.03^a

95.7 ± 5.00^a

< 0.001

NS

NS

Triglyceride mg/dL

100 ± 12.3

93.7 ± 8.30

81.7 ± 8.35

78.1 ± 7.24

NS

NS

NS

Glucose, mg/dL

179 ± 17.1^b

237 ± 10.9^a

190 ± 16.2^b

215 ± 10.1^ab

0.01

NS

NS