Interaction between the genetic risk score and dietary protein intake on cardiometabolic traits in Southeast Asian

Table 3 Interactions between GRS and lifestyle factors on cardio-metabolic traits

	Carbohydrate (%)	Protein (%)	Fat (%)	Fibre (g)	Physical activity
BMI (kg/m²)	0.961	0.282	0.721	0.876	0.362
WC (cm)	0.224	0.002	0.577	0.614	0.297
Log glucose (mg/dl)	0.882	0.751	0.732	0.833	0.106
Log insulin (mIU/L)	0.336	0.341	0.48	0.216	0.909
Log HbA1C (ng/ml)	0.766	0.638	0.935	0.162	0.626
Log triglycerides (mg/dl)	0.066	0.003	0.355	0.262	0.479
Log cholesterol (mg/dl)	0.081	0.021	0.261	0.583	0.308
Log HDL-C (mg/dl)	0.978	0.905	0.984	0.323	0.540
Log LDL-C (mg/dl)	0.266	0.337	0.431	0.896	0.721
Log SBP (mmHg)	0.156	0.291	0.208	0.872	0.644
Log DBP (mmHg)	0.966	0.815	0.732	0.292	0.743

Data are P values obtained from linear regression analysis adjusted for age, residential area and BMI when BMI is not an outcome. The analysis was performed on log-transformed variables
BMI body mass index, WC waist circumference, HbA1C glycated haemoglobin A1c, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, SBP systolic blood pressure, DBP diastolic blood pressure

ISSN: 1865-3499