Fig. 2

DNA methylation levels for probes in control adipocytes reveal a general decreasing level of DNA methylation for each time point. A total of 798 differentially methylated genes present the decreasing trend, but β values for 639 genes increase with time. Most changes occur between 192 and 384 h. b Change of expression (top) and methylation levels (bottom) during differentiation for the gene PRKCA. Dots represent the different replicates available for each time methylation. Different time points across differentiation are represented by different colors. a Methylation patterns during differentiation. Dots define averaged β values (absolute percentages of points)