Table 5 The ten most significant pathways from the NASFinder TFs analysis on the 1437 significant DMRs at 384 h are displayed. The p value, the Network Activity Score (NAS), the identified TF, and the DMRs involved in each pathway are added

BioCarta phospholipase C D1 in phospholipid-associated cell signaling

0.322

0.005

PRKCA

JUNB

BioCarta CBL-mediated ligand-induced downregulation of EGF receptors

0.191

0.008

PRKCA

MET

BioCarta activation of PKC through G protein-coupled receptor

0.186

0.003

PRKCA

NFKBIA

BioCarta apoptotic signaling in response to DNA damage

0.167

0.011

APAF1, BID, PRKCA

TP53

BioCarta role of MEF2D in T cell apoptosis

0.163

0.018

MEF2D, PRKCA

EP300

BioCarta FXR and LXR regulation of cholesterol metabolism

0.115

0.010

ABCA1, NR1H3

RXRA

BioCarta cadmium induces DNA synthesis and proliferation in macrophages

0.088

0.013

PRKCA

MYC

BioCarta TPO signaling pathway

0.064

0.029

PRKCA, STAT5A

STAT3

BioCarta effects of calcineurin in keratinocyte differentiation

0.060

0.022

PRKCA

SP3

Reactome regulation of gene expression by hypoxia-inducible factor

0.056

0.012

CITED2

HIF1A