Dietary BCAAs (mg/g protein) | GRS in classified mode | GRS in continuous mode | ||||||
---|---|---|---|---|---|---|---|---|
< 22 | 22–24 | ≥ 25 | P for Trend | P for interaction | Per 1 allele | P value | P for interaction | |
Total BCAAs |  |  |  |  | 0.001 |  |  | < 0.001 |
 T1 (n = 289) | 1 | 0.71 (0.34–1.36) | 0.63 (0.32–1.24) | 0.19 |  | 0.95 (0.88–1.01) | 0.11 |  |
 T2 (n = 290) | 1 | 1.00 (0.53–1.90) | 2.22 (1.12–4.12) | 0.012 |  | 1.10 (1.02–1.17) | 0.006 |  |
 T3 (n = 289) | 1 | 2.30 (1.19–4.46) | 2.98 (1.54–5.76) | 0.001 |  | 1.13 (1.06–1.21) | < 0.001 |  |
Isoleucine |  |  |  |  | < 0.001 |  |  | < 0.001 |
 T1 (n = 289) | 1 | 0.63 (0.32–1.22) | 0.58 (0.29–1.13) | 0.12 |  | 0.94 (0.88–1.01) | 0.08 |  |
 T2 (n = 290) | 1 | 1.15 (0.61–2.18) | 2.39 (1.29–4.44) | 0.006 |  | 1.10 (1.03–1.17) | 0.005 |  |
 T3 (n = 289) | 1 | 2.13 (1.11–4.07) | 2.95 (1.53–5.68) | 0.001 |  | 1.13 (1.06–1.21) | < 0.001 |  |
Leucine |  |  |  |  | 0.001 |  |  | < 0.001 |
 T1 (n = 289) | 1 | 0.71 (0.37–1.37) | 0.62 (0.32–1.23) | 0.18 |  | 0.94 (0.88–1.01) | 0.10 |  |
 T2 (n = 290) | 1 | 1.08 (0.57–2.04) | 2.26 (1.22–4.19) | 0.011 |  | 1.10 (1.03–1.17) | 0.006 |  |
 T3 (n = 289) | 1 | 2.16 (1.11–4.18) | 3.00 (1.56–5.81) | 0.001 |  | 1.14 (1.06–1.21) | < 0.001 |  |
Valine | Â | Â | Â | Â | 0.003 | Â | Â | 0.001 |
 T1 (n = 289) | 1 | 0.72 (0.37–1.39) | 0.78 (0.40–1.52) | 0.48 |  | 0.96 (0.90–1.03) | 0.25 |  |
 T2 (n = 290) | 1 | 1.12 (0.59–2.14) | 1.88 (1.01–3.50) | 0.046 |  | 1.09 (1.02–1.16) | 0.014 |  |
 T3 (n = 289) | 1 | 2.10 (1.08–4.08) | 2.95 (1.52–5.72) | 0.001 |  | 1.13 (1.05–1.20) | 0.001 |  |