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Fig. 1 | Genes & Nutrition

Fig. 1

From: TCONS_00230836 silencing restores stearic acid-induced β cell dysfunction through alleviating endoplasmic reticulum stress rather than apoptosis

Fig. 1

LncRNA TCONS_00230836 upregulation in stearic acid-treated β-TC6 cells and islets of mice fed a high-stearic-acid diet. a The studied lncRNA TCONS_00230836 with fold changes, p values, and genomic locations in the presence of stearic acid and palmitic acid by RNA sequencing, respectively. (n=3 per group) b qRT-PCR results verified that the level of the lncRNA TCONS_00230836 was elevated in stearic acid-treated β-TC6 cells. (n=4) c The expression of the lncRNA TCONS_00230836 was also increased in the islets (n=5) from mice fed a high-stearic-acid diet, as revealed by qRT-PCR. Ctrl control group, SA stearic acid, PA palmitic acid, HSD high-stearic-acid diet. **p < 0.01, versus the Ctrl group

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Genes & Nutrition

ISSN: 1865-3499

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