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Fig. 7 | Genes & Nutrition

Fig. 7

From: TCONS_00230836 silencing restores stearic acid-induced β cell dysfunction through alleviating endoplasmic reticulum stress rather than apoptosis

Fig. 7

Silencing lncRNA TCONS_00230836 did not markedly alter islet apoptosis exposure to stearic acid. a, b Assessment of cell viability in HSD mice islets treated with Smart Silencer for TCONS_00230836 by CCK8 assay and cell death by LDH measurement, separately. c Western blot analysis verifying the changes in the expression of cleaved-caspase3, cleaved-Parp1, and Bcl-2 after inhibition of the lncRNA TCONS_00230836. NS not significant, SA stearic acid, si-lnc836 Smart Silencer for lncRNA TCONS_00230836. n = 5 independent animal experiments per group. *p < 0.05, **p < 0.01 versus the control group; ^p < 0.05, ^^p < 0.01 versus the SA group

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