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Table 3 Haplotype analysis of CYP24A1 gene in PTB patients and controls

From: Association of vitamin D pathway genes polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population

Haplotype

PTB patients [n (%)]

Controls [n (%)]

P value

OR (95% CI)

rs2248359-rs2296241-rs927650-rs6013897

 CACT

27.92 (2.8)

38.05 (3.9)

0.211

0.729 (0.443, 1.199)

 CGCA

65.38 (6.7)

60.37 (6.2)

0.623

1.095 (0.762, 1.574)

 CGCT

294.59 (30.1)

323.30 (33.1)

0.178

0.875 (0.720, 1.063)

 CGTT

170.10 (17.4)

150.40 (15.4)

0.206

1.169 (0.918, 1.489)

 TACA

48.89 (5.0)

62.79 (6.4)

1.183

0.770 (0.523, 1.132)

 TACT

240.09 (24.5)

203.40 (20.8)

0.039

1.254 (1.012, 1.555)

 TATT

49.78 (5.1)

62.97 (6.4)

0.210

0.783 (0.533, 1.149)

  1. Global χ2 is 10.598, df=6 (frequency<0.03 in both control & case has been dropped)
  2. Fisher’s p value is 0.102