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Table 5 Haplotype analysis of CYP2R1 gene in PTB patients and controls

From: Association of vitamin D pathway genes polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population

Haplotype

PTB patients [n (%)]

Controls [n (%)]

P value

OR (95% CI)

rs12794714-rs10741657-rs7935792-rs1562902

 AGAT

364.57 (37.2)

347.56 (35.5)

0.381

1.087 (0.902, 1.311)

 GAAC

340.32 (34.7)

349.69 (35.8)

0.699

0.964 (0.798, 1.163)

 GGAT

92.51 (9.4)

124.85 (12.8)

0.021

0.715 (0.538, 0.952)

 GGCC

33.40 (3.4)

39.71 (4.1)

0.461

0.838 (0.524, 1.341)

 GGCT

95.74 (9.8)

68.28 (7.0)

0.023

1.455 (1.051, 2.013)

  1. Global χ2 is 10.485, df=5 (frequency<0.03 in both control and case has been dropped)
  2. Fisher’s p value is 0.033
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Genes & Nutrition

ISSN: 1865-3499

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