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Table 6 Haplotype analysis of GC gene in PTB patients and controls

From: Association of vitamin D pathway genes polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population

Haplotype

PTB patients [n (%)]

Controls [n (%)]

P value

OR (95% CI)

rs7041-rs3733359-rs16847024-rs4588

 AACG

123.94 (12.6)

122.66 (12.5)

0.916

1.014 (0.776, 1.326)

 AATG

93.08 (9.5)

126.88 (13.0)

0.016

0.706 (0.531, 0.938)

 AGCG

198.01 (20.2)

165.20 (16.9)

0.053

1.255 (0.997, 1.579)

 AGCT

317.50 (32.4)

296.95 (30.4)

0.297

1.108 (0.914, 1.343)

 CACG

47.17 (4.8)

65.29 (6.7)

0.080

0.709 (0.482, 1.044)

 CGCG

160.45 (16.4)

165.10 (16.9)

0.792

0.968 (0.763, 1.230)

  1. Global χ2 is 11.832, df=5 (frequency<0.03 in both control and case has been dropped)
  2. Fisher’s p value is 0.037