The association of circulating miR-191 and miR-375 expression levels with markers of insulin resistance in overweight children: an exploratory analysis of the I.Family Study

Table 3 Association between miRNAs and insulin sensitivity in boys and girls

	Boys (n = 27) Coefficient (95% CI)	p	Girls (n = 31) Coefficient (95% CI)	p
A) miR-191-3p
Insulin (pg/dl)	413.2 (309.8–516.6)	0.004	520.3 (436.0–604.6)	0.007
HOMA index	2.3 (1.4–3.2)	0.010	2.9 (1.8–3.4)	0.003
B) miR-375
Insulin (pg/dl)	444.2 (346,6–541.8)	0.003	459.5 (370.6–548.4)	0.009
HOMA index	2.5 (1.6–3.4)	0.009	2.6 (1.9–3.2)	0.034

95% CI 95% confidence interval. Covariates: country of origin, highest educational level of parents defined according to the International Standard Classification of Education (ISCED, 2011), puberty status, age, total energy intake (kcal/day), energy from fat (%), energy from CHO (%), energy from protein (%). Data are expressed as mean (95% confident intervals)

ISSN: 1865-3499