Table 2 Associations between inadequate vitamin D status and risk of premenstrual symptoms stratified by VDR genotype

Acne/skin blemish

0.89 (0.54, 1.48)

0.66

0.97 (0.54, 1.73)

0.91

0.83 (0.53, 1.32)

0.43

0.88 (0.52, 1.50)

0.63

0.67 (0.35, 1.29)

0.23

0.74 (0.35, 1.57)

0.44

Bloating/swelling/breast tenderness

1.18 (0.68, 2.07)

0.55

1.34 (0.71, 2.51)

0.37

0.60 (0.36, 1.00)

0.048

0.71 (0.39, 1.27)

0.24

0.77 (0.38, 1.58)

0.48

0.76 (0.34, 1.72)

0.51

Cramps

1.29 (0.74, 2.25)

0.38

1.17 (0.61, 2.24)

0.63

0.81 (0.48, 1.36)

0.42

0.93 (0.50, 1.74)

0.82

1.26 (0.53, 3.01)

0.60

1.88 (0.66, 5.33)

0.24

Mood swings/crying easily/irritability/angry outbursts

1.03 (0.57, 1.85)

0.92

1.08 (0.55, 2.11)

0.83

0.85 (0.52, 1.41)

0.54

0.88 (0.50, 1.58)

0.68

0.93 (0.47, 1.84)

0.84

0.89 (0.41, 1.94)

0.77

Increased appetite/food cravings

1.37 (0.81, 2.30)

0.24

1.62 (0.89, 2.94)

0.12

1.56 (0.98, 2.47)

0.060

1.78 (1.03, 3.07)

0.040

0.53 (0.27, 1.05)

0.070

0.48 (0.22, 1.04)

0.06

Fatigue

1.91 (1.15, 3.17)

0.013

2.53 (1.40, 4.56)

0.0021

1.06 (0.68, 1.67)

0.79

1.12 (0.66, 1.90)

0.67

0.63 (0.33, 1.20)

0.16

0.44 (0.20, 0.97)

0.04

Headache

0.87 (0.51, 1.48)

0.61

0.99 (0.53, 1.84)

0.98

1.36 (0.78, 2.37)

0.28

1.48 (0.78, 2.82)

0.23

0.63 (0.30, 1.30)

0.21

0.39 (0.15, 1.00)

0.05

Anxiety/tension/nervousness

1.16 (0.70, 1.91)

0.57

1.63 (0.92, 2.91)

0.097

1.38 (0.87, 2.21)

0.18

1.39 (0.81, 2.38)

0.24

0.80 (0.41, 1.60)

0.54

0.63 (0.28, 1.42)

0.27

Clumsiness

1.08 (0.58, 2.00)

0.81

1.55 (0.77, 3.15)

0.22

1.35 (0.68, 2.68)

0.39

1.49 (0.68, 3.29)

0.32

1.11 (0.44, 2.82)

0.82

0.88 (0.90, 2.62)

0.82

Confusion/difficulty concentrating/forgetfulness

1.58 (0.89, 2.79)

0.12

2.11 (1.09, 4.06)

0.026

2.10 (1.18, 3.76)

0.012

2.13 (1.10, 4.13)

0.026

2.22 (0.95, 5.24)

0.067

2.07 (0.78, 5.48)

0.14

Sexual desire/activity changes

1.34 (0.82, 2.21)

0.25

1.99 (1.09, 3.63)

0.025

1.04 (0.66, 1.65)

0.86

1.26 (0.73, 2.18)

0.41

1.10 (0.59, 2.08)

0.76

1.24 (0.59, 2.62)

0.57

Insomnia

1.46 (0.68, 3.16)

0.33

2.23 (0.92, 5.41)

0.077

0.73 (0.35, 1.51)

0.39

0.61 (0.26, 1.41)

0.24

1.63 (0.61, 4.33)

0.33

1.15 (0.38, 3.55)

0.80

Nausea

1.87 (0.88, 3.95)

0.10

2.44 (1.00, 5.95)

0.050

0.53 (0.27, 1.04)

0.067

0.59 (0.27, 1.28)

0.18

1.06 (0.45, 2.50)

0.90

1.48 (0.52, 4.16)

0.46

Depression

1.31 (0.75, 2.28)

0.34

1.84 (0.97, 3.48)

0.063

1.37 (0.83, 2.25)

0.22

1.63 (0.90, 2.94)

0.11

0.71 (0.36, 1.43)

0.34

0.67 (0.30, 1.49)

0.32

Desire to be alone

1.51 (0.89, 2.56)

0.13

2.22 (1.19, 4.13)

0.012

1.51 (0.94, 2.45)

0.092

1.43 (0.82, 2.48)

0.21

1.12 (0.58, 2.13)

0.74

1.14 (0.54, 2.42)

0.74