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Table 1 Demographic profiles about the selected AD and AD proxy phenotype GWAS datasets

From: Mendelian randomization to evaluate the effect of plasma vitamin C levels on the risk of Alzheimer’s disease

GWAS datasets

AD or AD proxy

Controls or proxy controls

N

% female

Mean AAO (s.d)

N

% female

Mean AAE (s.d)

IGAP ADGC

14,428

59.3

71.1 (17.3)

14,562

59.3

76.2 (9.9)

IGAP CHARGE

2137

67.3

82.6 (12)

13,474

55.8

76.7 (8.2)

IGAP EADI

2240

65

75.4 (9.1)

6631

60.6

78.9 (7.0)

IGAP GERAD

3177

64

73.0 (0.2)

7277

51.8

51.0 (0.1)

UK Biobank AD proxy

42,034

65.9

-

272,244

-

-

Maternal AD group from UK Biobank

27,696

100

-

260,980

-

-

Paternal AD group from UK Biobank

14,338

0

-

245,941

-

-

  1. AD Alzheimer’s disease, AAO age at onset, AAE age at examination