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Fig. 1 | Genes & Nutrition

Fig. 1

From: Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma

Fig. 1

PD-L1 expression in the TSCC samples and cell lines. A HE staining was used to evaluate TSCC pathology. All cancerous tissues were pathologically confirmed as TSCC. B The expression of PD-L1 was evaluated by IHC. The expression of PD-L1 was significantly upregulated in TSCC. C The expression of PD-L1 in TSCC versus normal tissue were measured by western blot. The former was significantly upregulated. D PD-L1 mRNA expression in SCC9, SCC25, and CAL27 cells was detected by qRT-PCR. E To elucidate the mechanisms of PD-L1 nonimmune signaling in SCC9, SCC25, and CAL27 cells, PD-L1 and downstream key molecules were systematically analyzed by western bolt. **P < 0.01, *P < 0.05

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