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Table 2 Results of significant association of genetic variants with metabolic syndrome and its components (waist circumference and systolic blood pressure) in Korean adultsa

From: Interactions between red and processed meat consumption and APOA5 gene variants associated with the incidence of metabolic syndrome in Korean adults

No.

SNP

Chr

Minor allele

MAF

Gene

Function

MetS (controls 5591; cases 2785)

Waist circumference

SBP

Cases

Controls

OR (95% CI)

Add p value

Beta ± SE

Add p value

Beta ± SE

Add p value

1

rs651821

11

C

0.350

0.278

APOA5

Intron

1.45 (1.32–1.58)

2.08 × 10−15

0.22 ± 0.17

0.201

0.53 ± 0.35

0.129

2

rs662799

11

G

0.349

0.278

APOA5

Intron

1.45 (1.32–1.58)

2.35 × 10−15

0.22 ± 0.17

0.211

0.53 ± 0.35

0.126

3

rs2075291

11

A

0.107

0.069

APOA5

Intron

1.70 (1.47–1.97)

1.42 × 10−12

0.43 ± 0.29

0.141

0.41 ± 0.58

0.480

4

rs75198898

11

A

0.107

0.069

ZPR1

Intron

1.69 (1.46–1.96)

2.25 × 10−12

0.38 ± 0.29

0.186

0.48 ± 0.58

0.404

5

rs113932726

11

T

0.107

0.069

ZPR1

Intron

1.69 (1.46–1.96)

2.25 × 10−12

0.38 ± 0.29

0.186

0.48 ± 0.58

0.404

6

rs3741297

11

T

0.107

0.070

ZPR1

Intron

1.69 (1.46–1.95)

2.97 × 10−12

0.41 ± 0.29

0.155

0.39 ± 0.58

0.498

7

rs74368849

11

A

0.107

0.071

BUD13

Intron

1.65 (1.42–1.90)

2.54 × 10−11

0.35 ± 0.29

0.221

0.39 ± 0.58

0.500

8

rs167012

5

C

0.421

0.366

FBXL17

Intron

1.29 (1.18–1.40)

1.52 × 10−8

0.31 ± 0.17

0.066

0.77 ± 0.33

0.020

  1. Abbreviations: SNP Single nucleotide polymorphism, Chr Chromosome, MAF Minor allele frequency, MetS Metabolic syndrome, OR Odds ratio, CI Confidence interval, SE Standard error, SBP Systolic blood pressure, DBP Diastolic blood pressure, FBG Fasting blood glucose, HDL High-density lipoprotein, Add Additive model
  2. aModels were adjusted for age, residential area, and sex