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Fig. 5 | Genes & Nutrition

Fig. 5

From: Vitamin C attenuates predisposition to high-fat diet-induced metabolic dysregulation in GLUT10-deficient mouse model

Fig. 5

AA supplementation reduces HFD-induced ectopic lipid accumulation in GLUT10G128E mice. Mice were treated as described in Fig. 1A. Data were collected from mice at the conclusion of feeding (20 weeks of age). AB AA supplementation reduces HFD-induced free fatty acid (FFA) levels and total cholesterol (TCHO) levels in GLUT10G128E mice. A FFA levels and B TCHO levels in serum were determined. CH AA supplementation rescues HFD-induced ectopic lipid accumulation in liver and iBAT. Representative photographs of C livers and D iBAT from experimental mice. Each square on the green mat is 1 cm × 1 cm. E Liver weights. F iBAT weights. H&E staining of G liver sections and H iBAT sections. The data are shown as mean ± SEM. Statistical significance was determined by one-way ANOVA followed by Tukey’s test for multiple comparisons. The compact letter display indicates significant differences in pairwise comparisons; groups with different letters are significantly different

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