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Table 3 Module gene composition

From: Altered macronutrient composition and genetics influence the complex transcriptional network associated with adiposity in the Collaborative Cross

Module colors BF% correlated genes Diet DEGs Strain DEGs GWAS obesity traits genes Total genes
Turquoise 564 268 2497 719 3319
Blue 108 85 499 104 716
Brown 104 80 659 142 687
Yellow 258 172 618 123 665
Green 113 30 363 71 440
Red 137 68 371 74 378
Black 75 72 263 75 345
Pink 80 102 151 43 206
Magenta 42 52 145 27 163
Purple 30 13 155 23 157
Greenyellow 27 16 102 10 107
Tan 35 33 63 20 79
Salmon 29 0 42 11 42
  1. WCGNA identified 13 gene modules each assigned an arbitrary color with the number of genes contained in each module ranging from 42 (salmon) to 3119 (turquoise). Each gene module showed variation in terms of the number of genes with expression significantly correlated with post-diet body fat (BF%), genes differentially expressed by diet, genes differentially expressed by strain, and genes associated with obesity traits in humans according to the GWAS catalog