Fig. 3
From: 25(OH)Vitamin D and autism spectrum disorder: genetic overlap and causality
A In the figure, the x-axis (SD units) represents the effect of SNP on 25(0H) D and the y-axis (log OR) represents the effect of SNP on ASD. Each black dot represents an individual SNP, and the line segment represents the 95% CI. The slopes of the 3 straight lines correspond to the causal estimates of the 3 MR methods, green for the IVW method, red for the MR-Egger method, and light blue for the weighted median method. B In the figure, the black dots represent the log OR of the ASD increase in standard deviation (SD) in 25(OH)D. The OR was generated using each SNP as a separate instrumental variable. C No single SNP significantly affects the conclusions, and the results are stable