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  1. Selenium (Se), a dietary trace metal essential for human health, is incorporated into ~25 selenoproteins including selenoprotein S (SelS) and the 15-kDa selenoprotein (Sep15) both of which have functions in th...

    Authors: Alison Sutherland, Dong-Hyun Kim, Caroline Relton, Yoon-Ok Ahn and John Hesketh
    Citation: Genes & Nutrition 2010 5:176
  2. Advances in genomics science and associated bioinformatics and technology mean that excellent tools are available for characterising human genotypes. At the same time, approaches for characterising individual ...

    Authors: Linda Penn, Heiner Boeing, Carol J. Boushey, Lars Ove Dragsted, Jim Kaput, Augustin Scalbert, Ailsa A. Welch and John C. Mathers
    Citation: Genes & Nutrition 2010 5:175
  3. The challenge of modern nutrition and health research is to identify food-based strategies promoting life-long optimal health and well-being. This research is complex because it exploits a multitude of bioacti...

    Authors: Ben van Ommen, Jildau Bouwman, Lars O. Dragsted, Christian A. Drevon, Ruan Elliott, Philip de Groot, Jim Kaput, John C. Mathers, Michael Müller, Fre Pepping, Jahn Saito, Augustin Scalbert, Marijana Radonjic, Philippe Rocca-Serra, Anthony Travis, Suzan Wopereis…
    Citation: Genes & Nutrition 2010 5:167
  4. Fructosamine-3-Kinase (FN3K) is an enzyme phosphorilating fructoselysine (FL) residues on glycated proteins, resulting in the production of protein-bound FL-3-phosphate. The pathological role of the non-enzyma...

    Authors: M. Notarnicola, Maria G. Caruso, V. Tutino, V. Guerra, S. Frisullo, D. F. Altomare and G. Misciagna
    Citation: Genes & Nutrition 2010 5:165
  5. A single high-fat challenge induces plasmatic pro-inflammatory and pro-oxidative responses in the postprandial state, even in healthy men. This period is also associated with vascular endothelial dysfunction, ...

    Authors: Nicolas Dejeans, Jeanette A. M. Maier, Igor Tauveron, Dragan Milenkovic and Andrzej Mazur
    Citation: Genes & Nutrition 2010 5:166
  6. After a general introduction, the main pathways of ethanol metabolism (alcohol dehydrogenase, catalase, coupling of catalase with NADPH oxidase and microsomal ethanol-oxidizing system) are shortly reviewed. Th...

    Authors: Mario Comporti, Cinzia Signorini, Silvia Leoncini, Concetta Gardi, Lucia Ciccoli, Anna Giardini, Daniela Vecchio and Beatrice Arezzini
    Citation: Genes & Nutrition 2009 5:159
  7. We examined co-localization of vanilloid receptor (VR1) with sweet receptors T1R2, T1R3, or bitter receptor T2R6 in taste receptor cells of rat circumvallate papillae. Tissue sections of rat circumvallate papi...

    Authors: Young Wha Moon, Jong-Ho Lee, Sang Bae Yoo and Jeong Won Jahng
    Citation: Genes & Nutrition 2009 5:164
  8. Genetic factors are strongly involved in the development of obesity, likely through the interactions of susceptibility genes with obesigenic environments, such as high-fat, high-sucrose (HFS) diets. Previously...

    Authors: Hyoung Yon Kim, Taryn P. Stewart, Brantley N. Wyatt, Nalin Siriwardhana, Arnold M. Saxton and Jung Han Kim
    Citation: Genes & Nutrition 2009 5:163
  9. Cold-exposure activates interscapular brown adipose tissue (IBAT) non-shivering thermogenesis that relies primarily on intensification of metabolic rate and uncoupling. During cold-acclimation, uncoupling in I...

    Authors: Vesna Petrović, Biljana Buzadžić, Aleksandra Korać and Bato Korać
    Citation: Genes & Nutrition 2009 5:162
  10. While the effects of chronic ethanol consumption on liver have been well studied and documented, its effect on the cardiovascular system is bimodal. Thus, moderate drinking in many population studies is relate...

    Authors: Raj Lakshman, Mamatha Garige, Maokai Gong, Leslie Leckey, Ravi Varatharajalu and Samir Zakhari
    Citation: Genes & Nutrition 2009 5:161
  11. Chronic ethanol ingestion, achieved by feeding ethanol at a constant rate using intragastric tube feeding, alters the expression of genes in the liver. This is done by epigenetic mechanisms, which depend on th...

    Authors: Jun Li, Fawzia Bardag-Gorce, Joan Oliva, Jennifer Dedes, Barbara A. French and Samuel W. French
    Citation: Genes & Nutrition 2009 5:158
  12. Angiogenesis is a process of new blood vessel formation from pre-existing ones. The most important steps in angiogenesis include detachment, proliferation, migration, homing and differentiation of vascular wal...

    Authors: Urszula Razny, Anna Polus, Beata Kiec-Wilk, Lukasz Wator, Jadwiga Hartwich, Jerzy Stachura, Romana Tomaszewska, Grzegorz Dyduch, Piotr Laidler, Gerd Schmitz, Regina Goralczyk, Karin Wertz, George Riss, Nicole L. W. Franssen-van Hal, Jaap Keijer and Aldona Dembinska-Kiec
    Citation: Genes & Nutrition 2009 5:160
  13. Research into the metabolism of fats may reveal potential targets for developing pharmaceutical approaches to obesity and related disorders. Such research may be limited, however, by the cost and time involved...

    Authors: Toshihisa Nomura, Makoto Horikawa, Satoru Shimamura, Teppei Hashimoto and Kazuichi Sakamoto
    Citation: Genes & Nutrition 2009 5:157
  14. Dietary guidelines aim to control fat intake and reduce cardiovascular risk but an important interindividual variability occurs among subjects. The objective was to investigate whether the response of lipid an...

    Authors: Ahd Hammoud, Marguerite Gastaldi, Matthieu Maillot, Charles S. Mercier, Catherine Defoort, Denis Lairon and Richard Planells
    Citation: Genes & Nutrition 2009 5:155
  15. As essential cofactor in many proteins and redox enzymes, copper and iron are involved in a wide range of biological processes. Mild dietary deficiency of metals represents an underestimated problem for human ...

    Authors: Alessandra Tosco, Bianca Fontanella, Rosa Danise, Luigi Cicatiello, Olì M. V. Grober, Maria Ravo, Alessandro Weisz and Liberato Marzullo
    Citation: Genes & Nutrition 2009 5:153
  16. Growing evidence indicates that inflammatory reactions play an important role in the pathogenesis of alcoholic liver disease (ALD). The implication of immunity in fueling chronic inflammation in ALD has emerge...

    Authors: Emanuele Albano and Matteo Vidali
    Citation: Genes & Nutrition 2009 5:151
  17. The long latency and high incidence of prostate carcinogenesis provides the opportunity to intervene with chemoprevention in order to prevent or eradicate prostate malignancies. We present here an overview of ...

    Authors: Marie-Hélène Teiten, François Gaascht, Serge Eifes, Mario Dicato and Marc Diederich
    Citation: Genes & Nutrition 2009 5:152
  18. The mechanisms by which alcohol causes cell injury are not clear. A major mechanism that is the focus of considerable research is the role of lipid peroxidation and oxidative stress in alcohol toxicity. Many p...

    Authors: Yongke Lu and Arthur I. Cederbaum
    Citation: Genes & Nutrition 2009 5:150
  19. Dysregulation of lipid and glucose metabolism in the postprandial state are recognised as important risk factors for the development of cardiovascular disease and type 2 diabetes. Our objective was to create a...

    Authors: Kim G. Jackson, Dave T. Clarke, Peter Murray, Julie A. Lovegrove, Brendan O’Malley, Anne M. Minihane and Christine M. Williams
    Citation: Genes & Nutrition 2009 5:149
  20. Consumer goods became increasingly personalised, particularly during the last half of the 20th century. Foods and food products have been added a new flavour in this consumer trends with increasingly personali...

    Authors: Dilip Ghosh
    Citation: Genes & Nutrition 2009 5:139
  21. Tea, the major source of dietary flavonoids, particularly the epicatechins, signifies the second most frequently consumed beverage worldwide, which varies its status from a simple ancient cultural drink to a n...

    Authors: Orly Weinreb, Tamar Amit, Silvia Mandel and Moussa B. H. Youdim
    Citation: Genes & Nutrition 2009 4:143
  22. A mild-to-moderate wine drinking has been linked with reduced cardiovascular, cerebrovascular, and peripheral vascular risk as well as reduced risk due to cancer. The reduced risk of cardiovascular disease ass...

    Authors: Istvan Lekli, Diptarka Ray and Dipak K. Das
    Citation: Genes & Nutrition 2009 5:145
  23. Salacia reticulata is a native plant of Sri Lanka. In the traditional medicine of Sri Lanka and India, Salacia reticulata bark is considered orally effective in the treatment of rheumatism, gonorrhea, skin diseas...

    Authors: Yuusuke Sekiguchi, Hiroshi Mano, Sachie Nakatani, Jun Shimizu and Masahiro Wada
    Citation: Genes & Nutrition 2009 5:144
  24. Emerging evidence suggests that a group of dietary-derived phytochemicals known as flavonoids are able to induce improvements in memory, learning and cognition. Flavonoids have been shown to modulate critical ...

    Authors: Catarina Rendeiro, Jeremy P. E. Spencer, David Vauzour, Laurie T. Butler, Judi A. Ellis and Claire M. Williams
    Citation: Genes & Nutrition 2009 4:137
  25. The nuclear factor (NF)-κB is a primary regulator of inflammatory responses and may be linked to pathology associated with obesity. We investigated the progression of NF-κB activity during a 12-week feeding pe...

    Authors: Harald Carlsen, Fred Haugen, Susanne Zadelaar, Robert Kleemann, Teake Kooistra, Christian A. Drevon and Rune Blomhoff
    Citation: Genes & Nutrition 2009 4:133
  26. Research over the last 5 years has firmly established that learning and memory abilities, as well as mood, can be influenced by diet, although the mechanisms by which diet modulates mental health are not well ...

    Authors: Doris Stangl and Sandrine Thuret
    Citation: Genes & Nutrition 2009 4:134
  27. Evidence in support of the neuroprotective effects of flavonoids has increased significantly in recent years, although to date much of this evidence has emerged from animal rather than human studies. Nonethele...

    Authors: Anna L. Macready, Orla B. Kennedy, Judi A. Ellis, Claire M. Williams, Jeremy P. E. Spencer and Laurie T. Butler
    Citation: Genes & Nutrition 2009 4:135
  28. All definitions of the terms ‘oxidative stress’ and ‘antioxidants’ implicate that oxidants are just damaging. However, there is increasing evidence that reactive oxygen species (ROS) are not only toxic but tha...

    Authors: Regina Brigelius-Flohé
    Citation: Genes & Nutrition 2009 4:131
  29. The aim of this study was to investigate the possible associations between insertion/deletion (ID) polymorphism in angiotensin-converting enzyme (ACE) (dbSNP rs 4646994) with the food intake and body compositi...

    Authors: Julie Bienertova-Vasku, Petr Bienert, Lenka Sablikova, Lenka Slovackova, Martin Forejt, Zlata Piskackova, Lenka Kucerova, Katerina Heczkova, Zuzana Brazdova and Anna Vasku
    Citation: Genes & Nutrition 2009 4:130
  30. Omega-3 fatty acids (FAs) are natural ligands of the peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor that modulates expression levels of genes involved in lipid metabolism. The L162V p...

    Authors: Iwona Rudkowska, Christophe Garenc, Patrick Couture and Marie-Claude Vohl
    Citation: Genes & Nutrition 2009 4:129
  31. Recent epidemiological data suggest that β-carotene may be protective against metabolic diseases in which adipose tissue plays a key role. Adipose tissue constitutes the major β-carotene storage tissue and its...

    Authors: Franck Tourniaire, Erwan Gouranton, Johannes von Lintig, Jaap Keijer, M. Luisa Bonet, Jaume Amengual, Georg Lietz and Jean-François Landrier
    Citation: Genes & Nutrition 2009 4:128
  32. Progenitor cells have been extensively studied and therapeutically applied in tissue reconstructive therapy. Stromal vascular fraction (SVF) cells, which are derived from adipose tissue, may represent a potent...

    Authors: Agnieszka Sliwa, A. Balwierz, B. Kiec-Wilk, A. Polus, A. Knapp and A. Dembinska-Kiec
    Citation: Genes & Nutrition 2009 4:127
  33. Folate is a B vitamin required for one-carbon transfer reactions including methylation of cell macromolecules including DNA and synthesis of the purines adenosine and guanosine and the pyrimidine thymidine. Ep...

    Authors: John C. Mathers
    Citation: Genes & Nutrition 2009 4:126
  34. Foetal growth is particularly sensitive to the protein content of the mother’s diet. Microarray data from the foetal liver of pregnant rats fed normal (HP) or reduced protein diets (LP) were compared by gene s...

    Authors: Christopher J. McNeil, Susan M. Hay, Garry J. Rucklidge, Martin D. Reid, Gary J. Duncan and William David Rees
    Citation: Genes & Nutrition 2009 4:125
  35. Alternatives to animal testing and the identification of reliable methods that may decrease the need for animals are currently the subject of intense investigation worldwide. Alternative testing procedures are...

    Authors: M. Penza, M. Jeremic, C. Montani, M. Unkila, L. Caimi, G. Mazzoleni and Diego Di Lorenzo
    Citation: Genes & Nutrition 2009 4:124
  36. Previous studies have illustrated the importance of leptin receptor (OB-Rb) mediated action on adipocytes in the regulation of body weight. The aim of the present study was to investigate in male and female ra...

    Authors: T. Priego, J. Sánchez, A. Palou and C. Picó
    Citation: Genes & Nutrition 2009 4:114

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