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  1. Authors: Michela Baccini, Eva-Maria Bachmaier, Annibale Biggeri, Mark V. Boekschoten, Freek G. Bouwman, Lorraine Brennan, Robert Caesar, Saverio Cinti, Susan L. Coort, Katie Crosley, Hannelore Daniel, Christian A. Drevon, Susan Duthie, Lars Eijssen, Ruan M. Elliott, Marjan van Erk…
    Citation: Genes & Nutrition 2008 3:102
  2. The goal of this study was to investigate the effect of a short-term nutritional intervention on gene expression in adipose tissue from lean and overweight subjects. Gene expression profiles were measured afte...

    Authors: Marjan J. van Erk, Wilrike J. Pasman, Heleen M. Wortelboer, Ben van Ommen and Henk F. J. Hendriks
    Citation: Genes & Nutrition 2008 3:96
  3. Flavonoids exert a multiplicity of neuroprotective actions within the brain, including a potential to protect neurons against injury induced by neurotoxins, an ability to suppress neuroinflammation, and the po...

    Authors: David Vauzour, Katerina Vafeiadou, Ana Rodriguez-Mateos, Catarina Rendeiro and Jeremy P. E. Spencer
    Citation: Genes & Nutrition 2008 3:91
  4. Human nutrition and metabolism may serve as the paradigm for the complex interplay of the genome with its environment. The concept of nutrigenomics now enables science with new tools and comprehensive analytic...

    Authors: Hannelore Daniel, Christian A. Drevon, Ulla I. Klein, Robert Kleemann and Ben van Ommen
    Citation: Genes & Nutrition 2008 3:89
  5. The aetiology of breast cancer is complex and multifactorial, and may include diet and xenobiotic compounds. A change in diet affects nutrient levels in blood, but to what extent diet can affect micronutrient ...

    Authors: Ferdinando Mannello, Gaetana A. Tonti and Franco Canestrari
    Citation: Genes & Nutrition 2008 3:87
  6. Nutrition science finds itself at a major crossroad. On the one hand we can continue the current path, which has resulted in some substantial advances, but also many conflicting messages which impair the trust...

    Authors: Christine M. Williams, Jose M. Ordovas, Dennis Lairon, John Hesketh, Georg Lietz, Mike Gibney and Ben van Ommen
    Citation: Genes & Nutrition 2008 3:86
  7. In quantifying the beneficial effect of dietary interventions in healthy subjects, nutrition research meets a number of new challenges. Inter individual variation in biomarker values often is larger than the e...

    Authors: Ben van Ommen, Jaap Keijer, Robert Kleemann, Ruan Elliott, Christian A. Drevon, Harry McArdle, Mike Gibney and Michael Müller
    Citation: Genes & Nutrition 2008 3:84
  8. Low plasma levels of high-density lipoprotein cholesterol (HDL-C) are identified as a risk factor for cardiovascular disease (CVD). Sexual dimorphism, however, is widely reported in both HDL-C and CVD, with th...

    Authors: M. J. Mosher, L. A. Lange, B. V. Howard, E. T. Lee, L. G. Best, R. R. Fabsitz, J. W. MacCluer and K. E. North
    Citation: Genes & Nutrition 2008 3:75
  9. Cancer cachexia is a syndrome characterized by high prevalence and multifactorial etiology. The pathophysiology of cancer-induced weight loss is mainly due to failure of food intake and to various metabolic ab...

    Authors: Attilio Giacosa and Mariangela Rondanelli
    Citation: Genes & Nutrition 2008 3:78
  10. The major soy-derived isoflavones such as genistein has been demonstrated to possess anticarcinogenic activity in animal model systems. The present study was designed to investigate the effects of isoflavone g...

    Authors: Maria Notarnicola, Caterina Messa, Antonella Orlando, Benedetta D’Attoma, Valeria Tutino, Rosemary Rivizzigno and Maria Gabriella Caruso
    Citation: Genes & Nutrition 2008 3:82
  11. Epidemiological and experimental studies suggest a protective role of estrogens against colorectal cancer. This effect seems to be mediated by their binding to estrogen receptor beta (ER-β), one of the two est...

    Authors: Michele Barone, Sabina Tanzi, Katia Lofano, Maria Principia Scavo, Raffaella Guido, Lucia Demarinis, Maria Beatrice Principi, Antongiulio Bucci and Alfredo Di Leo
    Citation: Genes & Nutrition 2008 3:81
  12. The border between health and disease is often set by a complex equilibrium between two elements, genetics on one hand, lifestyle on the other, To know it better, means to give new weapons, often crucial, in t...

    Authors: Licia Iacoviello, Iolanda Santimone, Maria Carmela Latella, Giovanni de Gaetano and Maria Benedetta Donati
    Citation: Genes & Nutrition 2008 3:79
  13. Colorectal cancer and myocardial infarction are associated at population level and in autoptic studies. Furthermore, they share many blood variables: cholesterol, triglycerides and HDL cholesterol, fructosamin...

    Authors: G. Misciagna, M. G. Caruso and M. Trevisan
    Citation: Genes & Nutrition 2008 3:80
  14. Tumor microenvironment is essential for tumor cell proliferation, angiogenesis, invasion and metastasis through its provision of survival signals, secretion of growth and pro-angiogenic factors, and direct adh...

    Authors: Domenico Ribatti and Angelo Vacca
    Citation: Genes & Nutrition 2008 3:76
  15. The blood glucose-lowering property of pinitol is mediated via the insulin signaling pathway. This study was carried out to evaluate the effects of soy pinitol on adipogenesis in a 3T3-L1 cell line; 3T3-L1 pre...

    Authors: Gyeong-Min Do, Myung-Sook Choi, Hye-Jin Kim, Myung-Nam Woo, Mi-Kyung Lee and Seon-Min Jeon
    Citation: Genes & Nutrition 2007 2:71
  16. Recent studies have revealed that β-cell dysfunction is an important factor in developing type 2 diabetes. β-cell dysfunction is related to impairment of the insulin/IGF-1 signaling cascade through insulin rec...

    Authors: Sun Min Park, Sang Mee Hong, So Ra Sung, Ji Eun Lee and Dae Young Kwon
    Citation: Genes & Nutrition 2007 2:65
  17. It has been reported that the gum resin of Boswellia serrata (BS), which has been shown to have antiinflammatory properties, might also have anticancer effects. This study examined the potential of BS as an antic...

    Authors: Hyung-Ryong Kim, Myung-Sunny Kim, Dae-Young Kwon, Soo-Wan Chae and Han-Jung Chae
    Citation: Genes & Nutrition 2007 2:72
  18. The aim of the present study was to investigate the anti-obesity effect of a mixture composed of Garcinia cambogia extract, soypeptide, and l-carnitine (1.2:0.3:0.02, w/w/w) in rats rendered obese by a high-fat d...

    Authors: Yun Jung Kim, Keun-Young Kim, Min Sun Kim, Jin Hee Lee, Kang Pyo Lee and Taesun Park
    Citation: Genes & Nutrition 2007 2:70
  19. In this study, we investigated the lipolytic effects of eicosapentaenoic acid (EPA) in 3T3-L1 adipocytes. The differentiated 3T3-L1 adipocytes were treated in a serum-free medium with 300 μM of EPA for 3, 6, 1...

    Authors: Mak-Soon Lee, In-Sook Kwun and Yangha Kim
    Citation: Genes & Nutrition 2007 2:68
  20. Resveratrol, one of polyphenols derived from red wine, has been shown to protect against cell death, possibly through the association with several signaling pathways. Currently numerous studies indicate that c...

    Authors: Jin-Taek Hwang, Dae Young Kwon, Ock Jin Park and Myung Sunny Kim
    Citation: Genes & Nutrition 2007 2:69
  21. Numerous studies have shown that the levels of matrix metalloproteinase (MMP)-2 and/or MMP-9 are associated with the invasive phenotypes of cancer cells. This study investigated the effects of caffeic acid phe...

    Authors: Ki Won Lee, Nam Joo Kang, Jong Hun Kim, Kyoung Mi Lee, Dong Eun Lee, Haeng Jeon Hur and Hyong Joo Lee
    Citation: Genes & Nutrition 2007 2:67
  22. Folate deficiency increases stroke risk. We examined whether folate deficiency affects platelet endothelial cell adhesion molecule-1 (PECAM-1), which is an immunoglobulin-associated cell adhesion molecule and ...

    Authors: Ki-Yeon Yoo, In Koo Hwang, Young Sup Kim, Dae Young Kwon and Moo Ho Won
    Citation: Genes & Nutrition 2007 2:64
  23. Bone undergoes continuous remodeling through bone formation and resorption, and maintaining the balance for skeletal rigidity. Bone resorption and loss are generally attributed to osteoclasts. Differentiation ...

    Authors: Yu Na Youn, Erang Lim, Nari Lee, Young Seop Kim, Min Seon Koo and Soon Young Choi
    Citation: Genes & Nutrition 2007 2:62
  24. The effect of Schisandra fructus extract (SFE) on doxorubicin (Dox)-induced cardiotoxicity was investigated in H9c2 cardiomyocytes. Dox, which is an antineoplastic drug known to induce cardiomyopathy possibly thr...

    Authors: Eun Hye Choi, Nari Lee, Hyun Jung Kim, Mi Kyung Kim, Sung-Gil Chi, Dae Young Kwon and Hyang Sook Chun
    Citation: Genes & Nutrition 2007 2:73
  25. This study investigated the effect of Cheonggukjang on mRNA levels of hepatic acyl-CoA synthase (ACS), carnitine palmitoyltransferase I (CPT-I), acyl-CoA oxidase (ACO) and uncoupling protein 2 (UCP2), and on seru...

    Authors: Ju-Ryoun Soh, Dong-Hwa Shin, Dae Young Kwon and Youn-Soo Cha
    Citation: Genes & Nutrition 2007 2:66

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