https://genesandnutrition.biomedcentral.com/articles/10.1186/s12263-016-0537-z https://genesandnutrition.biomedcentral.com/articles/10.1186/s12263-016-0536-0 https://genesandnutrition.biomedcentral.com/articles/10.1186/s12263-016-0534-2