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Fig. 4 | Genes & Nutrition

Fig. 4

From: Metabolic programming in pregnancy: studies in animal models

Fig. 4

Evidence of intergenerational effects on maternal protein restriction upon blood pressure. Pregnant rats were fed either control (CON) or Low Protein (LP) diets in utero. Offspring were all fed the same standard diet and were mated to produce a second generation without further dietary change. Blood pressure of this second generation was measured at 8 weeks of age. The resulting offspring had raised blood pressure. This F1 generation were crossed to yield the F2. Low-blood pressures were noted in the offspring of low protein exposed females mated with low protein exposed males, but the hypertensive phenotype was transmitted by these females if mated with a control male (*P < 0.05) [19]

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