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Review
The notion of uptake of active diet-derived small RNAs (sRNAs) in recipient organisms could have significant implications for our understanding of oral therapeutics and nutrition, for the safe use of RNA inter...
Genes & Nutrition 2017 12:13
Published on: 7 July 2017
Research
Transgenic expression of small RNAs is a prevalent approach in agrobiotechnology for the global enhancement of plant foods. Meanwhile, emerging studies have, on the one hand, emphasized the potential of transg...
Genes & Nutrition 2017 12:17
Published on: 7 July 2017
Research
A polymorphism in a gene may exert its effects on multiple phenotypes. The aim of this study is to explore the association of 10 metabolic syndrome candidate genes with excess weight and adiposity and evaluate...
Genes & Nutrition 2017 12:19
Published on: 4 July 2017
Discussion
In ancient lore, a bullet cast from silver is the only effective weapon against monsters. The uptake of active diet-derived microRNAs (miRNAs) in consumers may be the silver bullet long sought after in nutriti...
Genes & Nutrition 2017 12:15
Published on: 22 June 2017
Editorial
When a novel nutritional concept comes along, scientists become enthusiastic and start new explorations. In 2012, the field was enthralled with a study suggesting plant-based nucleic acid “information” acts as...
Genes & Nutrition 2017 12:16
Published on: 22 June 2017
Commentary
Extracellular vesicles deliver a variety of cargos to recipient cells, including the delivery of cargos in dietary vesicles from bovine milk to non-bovine species. The rate of discovery in this important line ...
Genes & Nutrition 2017 12:12
Published on: 22 June 2017
Review
It is widely accepted that metabolic disorders, such as obesity, are closely linked to lifestyle and diet. Recently, the central role played by the intestinal microbiota in human metabolism and in progression ...
Genes & Nutrition 2017 12:18
Published on: 15 June 2017
Review
Folic acid and its derivates, known as folates, are chemoprotective micronutrients of great interest because of their essential role in the maintenance of health and genomic integrity. The supplementation of f...
Genes & Nutrition 2017 12:14
Published on: 2 June 2017
Research
Gene expression profiles of intestinal mucosa of chickens and pigs fed over long-term periods (days/weeks) with a diet rich in rye and a diet supplemented with zinc, respectively, or of chickens after a one-da...
Genes & Nutrition 2017 12:11
Published on: 13 April 2017
Research
To elucidate the effects of altered dietary carbohydrate and fat balance on liver and adipose tissue transcriptomes, 3-week-old rats were fed three kinds of diets: low-, moderate-, and high-fat diets (L, M, an...
Genes & Nutrition 2017 12:10
Published on: 8 April 2017
Research
The dietary xanthophylls, lutein and zeaxanthin, accumulate in primate retina and brain, and emerging evidence indicates neural lutein content may be beneficial for cognition. Neural xanthophyll content in pri...
Genes & Nutrition 2017 12:9
Published on: 8 March 2017
Research
High-intensity exercise induces many metabolic responses. In is unknown whether the response in the peripheral blood mononuclear cells (PBMCs) reflects the response in skeletal muscle and whether mRNA expressi...
Genes & Nutrition 2017 12:8
Published on: 3 March 2017
Research
Inflammation plays a central role in chronic diseases occurring in the contemporary society. The health benefits of omega-3 (n-3) fatty acids (FAs), mostly eicosapentaenoic acid (EPA) and docosahexaenoic acid ...
Genes & Nutrition 2017 12:7
Published on: 21 February 2017
Review
Androgens, the main male sex steroids, are the critical factors responsible for the development of the male phenotype during embryogenesis and for the achievement of sexual maturation and puberty. In adulthood...
Genes & Nutrition 2017 12:6
Published on: 16 February 2017
Research
Vitamins and carotenoids are key micronutrients facilitating the maintenance of health, as evidenced by the increased risk of disease with low intake. Optimal phenotypic flexibility, i.e., the ability to respo...
Genes & Nutrition 2017 12:5
Published on: 8 February 2017
Research
The level of omega-6 and omega-3 polyunsaturated fatty acids can affect many cellular systems and function via nuclear receptors or the bioactive lipid regulation of gene expression. The objective of this stud...
Genes & Nutrition 2017 12:4
Published on: 31 January 2017
Editorial
The complex physiology of living organisms represents a challenge for mechanistic understanding of the action of dietary bioactives in the human body and of their possible role in health and disease. Animal, c...
Genes & Nutrition 2017 12:3
Published on: 25 January 2017
Research
Hepatic fatty acids (FAs) are modified through different metabolic pathways including elongation and desaturation. These processes are catalyzed by elongases and desaturases, respectively. Glucose, by transcri...
Genes & Nutrition 2017 12:2
Published on: 25 January 2017
Research
Epidemiological studies suggest that hyponutrition during the fetal period increases the risk of mental disorders such as attention deficit hyperactivity disorder and autism-spectrum disorder, which has been e...
Genes & Nutrition 2017 12:1
Published on: 19 January 2017
Research
We have previously reported that γ- and δ-tocotrienols (γ- and δ-T3) induce gene expression and apoptosis in human breast cancer cells (MDA-MB-231 and MCF-7). This effect is mediated, at least in part, by a sp...
Genes & Nutrition 2016 11:32
Published on: 23 December 2016
Erratum
Genes & Nutrition 2016 11:31
Published on: 23 November 2016
The original article was published in Genes & Nutrition 2015 10:41
Research
Obesity is known to increase the risk of colorectal cancer. However, mechanisms underlying the pathogenesis of obesity-induced colorectal cancer are not completely understood. The purposes of this study were t...
Genes & Nutrition 2016 11:30
Published on: 22 November 2016
Research
The Nile rat (NR, Arvicanthis niloticus) is a model of carbohydrate-induced type 2 diabetes mellitus (T2DM) and the metabolic syndrome. A previous study found that palm fruit juice (PFJ) delayed or prevented diab...
Genes & Nutrition 2016 11:29
Published on: 22 October 2016
Research
The kidney is a major organ in which fluid balance and waste excretion is regulated. For the kidney to achieve maturity with functions, normal renal developmental processes need to occur. Comprehensive genetic...
Genes & Nutrition 2016 11:28
Published on: 20 October 2016
Research
Fetal exposure to a maternal low protein diet during rat pregnancy is associated with hypertension, renal dysfunction and metabolic disturbance in adult life. These effects are present when dietary manipulatio...
Genes & Nutrition 2016 11:27
Published on: 12 October 2016
Genes & Nutrition is affiliated with the European Nutrigenomics Organisation (NuGO). NuGO is an association of universities and research institutes focusing on the joint development of the research area of molecular nutrition, personalized nutrition, nutrigenomics and nutritional systems biology.
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