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  1. Content type: Review

    Biomarkers are an efficient means to examine intakes or exposures and their biological effects and to assess system susceptibility. Aided by novel profiling technologies, the biomarker research field is underg...

    Authors: Qian Gao, Giulia Praticò, Augustin Scalbert, Guy Vergères, Marjukka Kolehmainen, Claudine Manach, Lorraine Brennan, Lydia A. Afman, David S. Wishart, Cristina Andres-Lacueva, Mar Garcia-Aloy, Hans Verhagen, Edith J. M. Feskens and Lars O. Dragsted

    Citation: Genes & Nutrition 2017 12:34

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  2. Content type: Research

    The inverse relationship between exercise capacity and its variation over time and both cardiovascular and all-cause mortality suggests the existence of an etiological nexus between cardiometabolic diseases an...

    Authors: Natalia Gomes Gonçalves, Stephanie Heffer Cavaletti, Carlos Augusto Pasqualucci, Milton Arruda Martins and Chin Jia Lin

    Citation: Genes & Nutrition 2017 12:33

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  3. Content type: Research

    A key feature of metabolic health is the ability to adapt upon dietary perturbations. A systemic review defined an optimal nutritional challenge test, the “PhenFlex test” (PFT). Recently, it has been shown tha...

    Authors: T. J. van den Broek, G. C. M. Bakker, C. M. Rubingh, S. Bijlsma, J. H. M. Stroeve, B. van Ommen, M. J. van Erk and S. Wopereis

    Citation: Genes & Nutrition 2017 12:32

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  4. Content type: Research

    We investigated whether the long-term consumption of a symbiotic formulation with Lactobacillus fermentum (probiotic) and β-glucan from cauliflower mushroom (prebiotic) would delay the progression of post-menopau...

    Authors: Seong-Yeop Jeong, Suna Kang, Cao Shi Hua, Zhang Ting and Sunmin Park

    Citation: Genes & Nutrition 2017 12:31

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  5. Content type: Research

    The solute carrier family 30 member 8 gene (SLC30A8) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in SLC30A8 is associated with an ...

    Authors: Isabel Drake, George Hindy, Ulrika Ericson and Marju Orho-Melander

    Citation: Genes & Nutrition 2017 12:30

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  6. Content type: Review

    A large number of genome-wide association studies, transferability studies, and candidate gene studies performed in diverse populations around the world have identified gene variants that are associated with c...

    Authors: Joseph J. Castillo, Robert A. Orlando and William S. Garver

    Citation: Genes & Nutrition 2017 12:29

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  7. Content type: Research

    Obesity is a complex pathology associated with dysbiosis, metabolic alterations, and low-grade chronic inflammation promoted by immune cells, infiltrating and populating the adipose tissue. Probiotic supplemen...

    Authors: Marianna Roselli, Chiara Devirgiliis, Paola Zinno, Barbara Guantario, Alberto Finamore, Rita Rami and Giuditta Perozzi

    Citation: Genes & Nutrition 2017 12:25

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  8. Content type: Review

    Obesity, a major cause of death and disability, is increasing worldwide. Obesity is characterized by a chronic, low-grade inflammatory state which is suggested to play a critical role in the development of obe...

    Authors: Vibeke H. Telle-Hansen, Jacob J. Christensen, Stine M. Ulven and Kirsten B. Holven

    Citation: Genes & Nutrition 2017 12:26

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  9. Content type: Review

    Dietary supplementation of essential amino acids (EAAs) has been shown to promote healthspan. EAAs regulate, in fact, glucose and lipid metabolism and energy balance, increase mitochondrial biogenesis, and mai...

    Authors: Francesco Bifari, Chiara Ruocco, Ilaria Decimo, Guido Fumagalli, Alessandra Valerio and Enzo Nisoli

    Citation: Genes & Nutrition 2017 12:27

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  10. Content type: Research

    During evolution, humans colonized different ecological niches and adopted a variety of subsistence strategies that gave rise to diverse selective pressures acting across the genome. Environmentally induced se...

    Authors: Silvia Parolo, Sébastien Lacroix, Jim Kaput and Marie-Pier Scott-Boyer

    Citation: Genes & Nutrition 2017 12:28

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  11. Content type: Commentary

    In the dietary and health research area, biomarkers are extensively used for multiple purposes. These include biomarkers of dietary intake and nutrient status, biomarkers used to measure the biological effects...

    Authors: Lars O. Dragsted, Qian Gao, Giulia Praticò, Claudine Manach, David S. Wishart, Augustin Scalbert and Edith J. M. Feskens

    Citation: Genes & Nutrition 2017 12:24

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  12. Content type: Review

    In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been the object of intensive research. miRNAs have emerged as key mediators of metabolic processes, playing crucial roles in mai...

    Authors: Giuseppe Iacomino and Alfonso Siani

    Citation: Genes & Nutrition 2017 12:23

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  13. Content type: Research

    Methionine, a central molecule in one-carbon metabolism, is an essential amino acid required for normal growth and development. Despite its importance to biological systems, methionine is toxic when administer...

    Authors: Isabelle R. Miousse, Rupak Pathak, Sarita Garg, Charles M. Skinner, Stepan Melnyk, Oleksandra Pavliv, Howard Hendrickson, Reid D. Landes, Annie Lumen, Alan J. Tackett, Nicolaas E.P. Deutz, Martin Hauer-Jensen and Igor Koturbash

    Citation: Genes & Nutrition 2017 12:22

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  14. Content type: Research

    A key feature of metabolic health is the ability to adapt upon dietary perturbations. Recently, it was shown that metabolic challenge tests in combination with the new generation biomarkers allow the simultane...

    Authors: Suzan Wopereis, Johanna H. M. Stroeve, Annette Stafleu, Gertruud C. M. Bakker, Jacobus Burggraaf, Marjan J. van Erk, Linette Pellis, Ruud Boessen, Alwine A. F. Kardinaal and Ben van Ommen

    Citation: Genes & Nutrition 2017 12:21

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  15. Content type: Research

    The ability to digest lactose after weaning, namely, lactase persistence (LP), is encoded by polymorphisms in the MCM6 gene and varies widely in frequency among different human populations. Although, evolution of...

    Authors: Yosra Ben Halima, Rym Kefi, Marco Sazzini, Cristina Giuliani, Sara De Fanti, Chokri Nouali, Majdi Nagara, Giacomo Mengozzi, Sahar Elouej, Abdelmajid Abid, Henda Jamoussi, Lotfi Chouchane, Giovanni Romeo, Sonia Abdelhak and Donata Luiselli

    Citation: Genes & Nutrition 2017 12:20

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  16. Content type: Research

    A polymorphism in a gene may exert its effects on multiple phenotypes. The aim of this study is to explore the association of 10 metabolic syndrome candidate genes with excess weight and adiposity and evaluate...

    Authors: Angélica María Muñoz, Claudia María Velásquez, Gloria María Agudelo, Rosa Magdalena Uscátegui, Alejandro Estrada, Fredy Alonso Patiño, Beatriz Elena Parra, María Victoria Parra and Gabriel Bedoya

    Citation: Genes & Nutrition 2017 12:19

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  17. Content type: Discussion

    In ancient lore, a bullet cast from silver is the only effective weapon against monsters. The uptake of active diet-derived microRNAs (miRNAs) in consumers may be the silver bullet long sought after in nutriti...

    Authors: Kenneth W. Witwer and Chen-Yu Zhang

    Citation: Genes & Nutrition 2017 12:15

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  18. Content type: Editorial

    When a novel nutritional concept comes along, scientists become enthusiastic and start new explorations. In 2012, the field was enthralled with a study suggesting plant-based nucleic acid “information” acts as...

    Authors: Kendal D. Hirschi

    Citation: Genes & Nutrition 2017 12:16

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  19. Content type: Commentary

    Extracellular vesicles deliver a variety of cargos to recipient cells, including the delivery of cargos in dietary vesicles from bovine milk to non-bovine species. The rate of discovery in this important line ...

    Authors: Janos Zempleni

    Citation: Genes & Nutrition 2017 12:12

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  20. Content type: Review

    It is widely accepted that metabolic disorders, such as obesity, are closely linked to lifestyle and diet. Recently, the central role played by the intestinal microbiota in human metabolism and in progression ...

    Authors: Sabrina Duranti, Chiara Ferrario, Douwe van Sinderen, Marco Ventura and Francesca Turroni

    Citation: Genes & Nutrition 2017 12:18

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  21. Content type: Research

    Gene expression profiles of intestinal mucosa of chickens and pigs fed over long-term periods (days/weeks) with a diet rich in rye and a diet supplemented with zinc, respectively, or of chickens after a one-da...

    Authors: Marcel Hulst, Alfons Jansman, Ilonka Wijers, Arjan Hoekman, Stéphanie Vastenhouw, Marinus van Krimpen, Mari Smits and Dirkjan Schokker

    Citation: Genes & Nutrition 2017 12:11

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  22. Content type: Research

    To elucidate the effects of altered dietary carbohydrate and fat balance on liver and adipose tissue transcriptomes, 3-week-old rats were fed three kinds of diets: low-, moderate-, and high-fat diets (L, M, an...

    Authors: Mitsuru Tanaka, Akihito Yasuoka, Manae Shimizu, Yoshikazu Saito, Kei Kumakura, Tomiko Asakura and Toshitada Nagai

    Citation: Genes & Nutrition 2017 12:10

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