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  1. Cardiometabolic diseases are complex traits which are influenced by several single nucleotide polymorphisms (SNPs). Thus, analysing the combined effects of multiple gene variants might provide a better underst...

    Authors: Sooad Alsulami, A. S. Aji, U. Ariyasra, S. R. Sari, N. Tasrif, F. F. Yani, J. A. Lovegrove, I. R. Sudji, N. I. Lipoeto and K. S. Vimaleswaran

    Citation: Genes & Nutrition 2020 15:19

    Content type: Research

    Published on:

  2. This study evaluated gene-nutrition interactions between folate and the aberrant DNA methylation of tumor suppressor genes in different stages of carcinogenesis of esophageal squamous cell carcinoma (ESCC).

    Authors: Shaokang Wang, Da Pan, Ming Su, Guiling Huang and Guiju Sun

    Citation: Genes & Nutrition 2020 15:18

    Content type: Research

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  3. Grapes and berries are two types of widely consumed fruits characterized by a high content in different phytochemicals. However, their accurate dietary assessment is particularly arduous, because of the alread...

    Authors: M. Ulaszewska, M. Garcia-Aloy, N. Vázquez-Manjarrez, M. T. Soria-Florido, R. Llorach, F. Mattivi and C. Manach

    Citation: Genes & Nutrition 2020 15:17

    Content type: Review

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  4. Nutrigenomics is an emerging science that studies the relationship between genes, diet and nutrients that can help prevent chronic disease. The development of this science depends on whether the public accept ...

    Authors: Muhammad Adzran Che Mustapa, Latifah Amin and Lynn J. Frewer

    Citation: Genes & Nutrition 2020 15:16

    Content type: Research

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  5. Obesity is characterized by low-grade chronic inflammation and an excess of adipose tissue. The ASC gene encodes a protein that is part of the NLRP3 inflammasome, a cytosolic multiprotein complex that is associat...

    Authors: Elisa Barrón-Cabrera, Karina González-Becerra, Gustavo Rosales-Chávez, Alondra Mora-Jiménez, Iván Hernández-Cañaveral and Erika Martínez-López

    Citation: Genes & Nutrition 2020 15:15

    Content type: Research

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  6. Testosterone deficiency in men is clinically associated with the development of metabolic syndrome, which manifests as obesity, hepatic steatosis, and type-2 diabetes. We investigated the effects of castration...

    Authors: Myunggi Baik, Jin Young Jeong, Seung Ju Park, Seon Pil Yoo, Jin Oh. Lee, Jae Sung Lee, Md Najmul Haque and Hyun-Jeong Lee

    Citation: Genes & Nutrition 2020 15:14

    Content type: Research

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  7. The association with obesity of a common variant near the melanocortin-4 receptor (MC4R) gene (rs17782313) has been indicated in various studies. Adherence to dietary quality indices also have shown to have po...

    Authors: Mahdieh Khodarahmi, Mohammad Asghari Jafarabadi and Mahdieh Abbasalizad Farhangi

    Citation: Genes & Nutrition 2020 15:13

    Content type: Research

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  8. Adiponectin and resistin are typically secreted by the adipose tissue and are abnormally expressed in obesity. However, the underlying influential factors and mechanisms are to be elucidated. It is well known ...

    Authors: Hongyang Yao, Chaonan Fan, Yuanyuan Lu, Xiuqin Fan, Lulu Xia, Ping Li, Rui Wang, Tiantian Tang, Yuanyuan Wang and Kemin Qi

    Citation: Genes & Nutrition 2020 15:12

    Content type: Research

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  9. Consumption of fruit and vegetable is a key component of a healthy and sustainable diet. However, their accurate dietary assessment remains a challenge. Due to errors in self-reporting methods, the available d...

    Authors: N. Vázquez-Manjarrez, M. Ulaszewska, M. Garcia-Aloy, F. Mattivi, G. Praticò, L. O. Dragsted and C. Manach

    Citation: Genes & Nutrition 2020 15:11

    Content type: Review

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  10. We previously built a genetic risk score (GRS) highly predictive of the plasma triglyceride (TG) response to an omega-3 fatty acid (n-3 FA) supplementation from marine sources. The objective of the present stu...

    Authors: Bastien Vallée Marcotte, Janie Allaire, Frédéric Guénard, Juan de Toro-Martín, Patrick Couture, Benoît Lamarche and Marie-Claude Vohl

    Citation: Genes & Nutrition 2020 15:10

    Content type: Research

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  11. The endocannabinoid system (ECS) overactivation, associated with increased inflammatory process, may act as a risk factor for coronary artery disease (CAD). Dietary fat may influence the ECS tone. The aim of t...

    Authors: Sevda Saleh-Ghadimi, Mohammad Alizadeh, Hamed Jafari-Vayghan, Masoud Darabi, Ali Golmohammadi and Sorayya Kheirouri

    Citation: Genes & Nutrition 2020 15:9

    Content type: Research

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  12. MicroRNAs are emerging as new mediators in the regulation of adipocyte physiology and have been approved to play a role in obesity. Despite several studies have focused on microRNA expression profiles and func...

    Authors: Elham M. Youssef, Asmaa M. Elfiky, BanglySoliman, Nourhan Abu-Shahba and Mahmoud M. Elhefnawi

    Citation: Genes & Nutrition 2020 15:8

    Content type: Research

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  13. Numerous studies acknowledged the importance of an adequate vegetable consumption for human health. However, current methods to estimate vegetable intake are often prone to measurement errors due to self-repor...

    Authors: Elske M. Brouwer-Brolsma, Beate Brandl, Marion E. C. Buso, Thomas Skurk and Claudine Manach

    Citation: Genes & Nutrition 2020 15:7

    Content type: Review

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  14. The premature activation of digestive enzyme zymogens within pancreatic acinar cells is an important early feature of acute pancreatitis. Supraphysiological concentrations of cholecystokinin (CCK) cause intrap...

    Authors: Yeeun Park, Leeyeon Ku, Joo Weon Lim and Hyeyoung Kim

    Citation: Genes & Nutrition 2020 15:6

    Content type: Research

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  15. The frequency of vitamin D-associated gene variants appear to reflect changes in long-term ultraviolet B radiation (UVB) environment, indicating interactions exist between the primary determinant of vitamin D ...

    Authors: Patrice Jones, Mark Lucock, George Chaplin, Nina G. Jablonski, Martin Veysey, Christopher Scarlett and Emma Beckett

    Citation: Genes & Nutrition 2020 15:5

    Content type: Research

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  16. Following publication of the original article [1], the authors flagged that the ‘Availability of data and materials’ declaration is incomplete.

    Authors: Francesca Vacca, Amilcare Barca, Ana S. Gomes, Aurora Mazzei, Barbara Piccinni, Raffaella Cinquetti, Gianmarco Del Vecchio, Alessandro Romano, Ivar Rønnestad, Elena Bossi and Tiziano Verri

    Citation: Genes & Nutrition 2020 15:3

    Content type: Correction

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    The original article was published in Genes & Nutrition 2019 14:33

  17. Metabolic inflexibility is a characteristic of insulin resistance, limiting the ability to transiently regulate oxidative metabolism and gene expression in response to nutrient availability. Little is known of...

    Authors: F. Ramzan, R. F. D’Souza, B. R. Durainayagam, A. M. Milan, N. C. Roy, M. C. Kruger, C. J. Henry, C. J. Mitchell and D. Cameron-Smith

    Citation: Genes & Nutrition 2020 15:2

    Content type: Research

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  18. Excessive intake of carbohydrates and fats causes over-nutrition, leading to a variety of diseases and complications. Here, we characterized the effects of different types of sugar and lipids on the growth and...

    Authors: Xiong Wang, Lin Zhang, Lei Zhang, Wenli Wang, Sihan Wei, Jie Wang, Huilian Che and Yali Zhang

    Citation: Genes & Nutrition 2020 15:1

    Content type: Research

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  19. Meat, including fish and shellfish, represents a valuable constituent of most balanced diets. Consumption of different types of meat and fish has been associated with both beneficial and adverse health effects...

    Authors: Cătălina Cuparencu, Giulia Praticó, Lieselot Y. Hemeryck, Pedapati S. C. Sri Harsha, Stefania Noerman, Caroline Rombouts, Muyao Xi, Lynn Vanhaecke, Kati Hanhineva, Lorraine Brennan and Lars O. Dragsted

    Citation: Genes & Nutrition 2019 14:35

    Content type: Review

    Published on:

  20. This review investigates the current state of nutrigenomics in the zebrafish animal models. The zebrafish animal model has been used extensively in the study of disease onset and progression and associated mol...

    Authors: Michael B. Williams and Stephen A. Watts

    Citation: Genes & Nutrition 2019 14:34

    Content type: Review

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  21. Peptide transporter 1 (PepT1, alias Slc15a1) mediates the uptake of dietary di/tripeptides in all vertebrates. However, in teleost fish, more than one PepT1-type transporter might function, due to specific whole ...

    Authors: Francesca Vacca, Amilcare Barca, Ana S. Gomes, Aurora Mazzei, Barbara Piccinni, Raffaella Cinquetti, Gianmarco Del Vecchio, Alessandro Romano, Ivar Rønnestad, Elena Bossi and Tiziano Verri

    Citation: Genes & Nutrition 2019 14:33

    Content type: Research

    Published on:

    The Correction to this article has been published in Genes & Nutrition 2020 15:3

  22. Adequate protein intake among older adults is associated with better health outcomes such as immune function and metabolic regulation of skeletal muscle, but conflicting results make it difficult to define the...

    Authors: Gyrd O. Gjevestad, Kirsten B. Holven, Amanda Rundblad, Arnar Flatberg, Mari Myhrstad, Karina Karlsen, Shivaprakash J. Mutt, Karl-Heinz Herzig, Inger Ottestad and Stine M. Ulven

    Citation: Genes & Nutrition 2019 14:32

    Content type: Research

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  23. Globally, obesity is on the rise with ~ 30% of the world’s population now obese, and childhood obesity is following similar trends. Childhood obesity has been associated with numerous chronic conditions, inclu...

    Authors: Matthew R. McCann and Anusha Ratneswaran

    Citation: Genes & Nutrition 2019 14:31

    Content type: Review

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  24. Cereal foods are major contributors to the daily energy, protein, and dietary fiber intake all over the world. The role of cereals in human health is dependent on whether they are consumed as refined or whole ...

    Authors: Rikard Landberg, Kati Hanhineva, Kieran Tuohy, Mar Garcia-Aloy, Izabela Biskup, Rafael Llorach, Xiaofei Yin, Lorraine Brennan and Marjukka Kolehmainen

    Citation: Genes & Nutrition 2019 14:28

    Content type: Review

    Published on:

  25. Metabolic flexibility is the ability of an organism to switch between substrates for energy metabolism, in response to the changing nutritional state and needs of the organism. On the cellular level, metabolic...

    Authors: Samar HK Tareen, Martina Kutmon, Ilja CW Arts, Theo M de Kok, Chris T Evelo and Michiel E Adriaens

    Citation: Genes & Nutrition 2019 14:27

    Content type: Research

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  26. Low vitamin B12 concentrations have been associated with major clinical outcomes, including adiposity, in Indian populations. The Fat mass and obesity-associated gene (FTO) is an established obesity-susceptibilit...

    Authors: Shelini Surendran, Ramamoorthy Jayashri, Lauren Drysdale, Dhanasekaran Bodhini, Nagarajan Lakshmipriya, Coimbatore Subramanian Shanthi Rani, Vasudevan Sudha, Julie A. Lovegrove, Ranjit M. Anjana, Viswanathan Mohan, Venkatesan Radha, Rajendra Pradeepa and Karani S. Vimaleswaran

    Citation: Genes & Nutrition 2019 14:26

    Content type: Research

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  27. Seaweeds are marine macroalgae, some of which are edible. They are rich in specific dietary fibers and also contain other characteristic biological constituents. Biological activities have been investigated ma...

    Authors: Muyao Xi and Lars O. Dragsted

    Citation: Genes & Nutrition 2019 14:24

    Content type: Review

    Published on:

  28. The mechanism of high ambient temperature affecting meat quality is not clear till now. This study investigated the effect of high ambient temperature on meat quality and nutrition metabolism in finishing pigs.

    Authors: Xianyong Ma, Li Wang, Zibiao Shi, Wei Chen, Xuefen Yang, Youjun Hu, Chuntian Zheng and Zongyong Jiang

    Citation: Genes & Nutrition 2019 14:23

    Content type: Research

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  29. High protein intake may promote angiogenesis giving support to the development of metastasis according to the experimental data. However, nutritional epidemiologic evidence is inconsistent with metastasis. The...

    Authors: Ali Shokri, Saeed Pirouzpanah, Mitra Foroutan-Ghaznavi, Vahid Montazeri, Ashraf Fakhrjou, Hojjatollah Nozad-Charoudeh and Gholamreza Tavoosidana

    Citation: Genes & Nutrition 2019 14:22

    Content type: Research

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  30. Japan is traditionally a country with one of the highest levels of fish consumption worldwide, although the westernization of the Japanese diet has resulted in the reduction of fish consumption. A recent meta-...

    Authors: Maki Igarashi, Shun Nogawa, Kaoru Kawafune, Tsuyoshi Hachiya, Shoko Takahashi, Huijuan Jia, Kenji Saito and Hisanori Kato

    Citation: Genes & Nutrition 2019 14:21

    Content type: Research

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  31. Evidence suggests that prenatal exposure to n-3 long-chain polyunsaturated fatty acids (LCPUFA) reduces the incidence of allergic disease in children. LCPUFAs are produced from dietary precursors catalyzed by des...

    Authors: Purevsuren Losol, Faisal I. Rezwan, Veeresh K. Patil, Carina Venter, Susan Ewart, Hongmei Zhang, S. Hasan Arshad, Wilfried Karmaus and John W. Holloway

    Citation: Genes & Nutrition 2019 14:20

    Content type: Research

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  32. A low-protein diet increases the expression and circulating concentration of FGF21. FGF21 stimulates the browning process of WAT by enhancing the expression of UCP1 coupled with an increase in PGC1α. Interesti...

    Authors: Gabriela Alemán, Ana Laura Castro, Ana Vigil-Martínez, Ivan Torre-Villalvazo, Andrea Díaz-Villaseñor, Lilia G. Noriega, Isabel Medina-Vera, Guillermo Ordáz, Nimbe Torres and Armando R. Tovar

    Citation: Genes & Nutrition 2019 14:19

    Content type: Research

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  33. Culinary herbs and spices have been used as both food flavoring and food preservative agents for centuries. Moreover, due to their known and presumptive health benefits, herbs and spices have also been used in...

    Authors: Rosa Vázquez-Fresno, Albert Remus R. Rosana, Tanvir Sajed, Tuviere Onookome-Okome, Noah A. Wishart and David S. Wishart

    Citation: Genes & Nutrition 2019 14:18

    Content type: Review

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  34. Studies have shown that the effects of maternal nutrition exposure during gestation influence metabolic risk in early life through an epigenetic mechanism. Low glycaemic index (GI) diets benefit both maternal ...

    Authors: Weili Yan, Yi Zhang, Liping Wang, Wenhong Yang, Chunying Li, Liling Wang, Ping Gu, Yingqian Xia, Juhua Yan, Ying Shen, Qian Zhao, Dayan Niu, Kai Mu and Yuan Jiang

    Citation: Genes & Nutrition 2019 14:17

    Content type: Research

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  35. Variability in circulating carotenoids may be attributable to several factors including, among others, genetic variants and lipid profile. However, relatively few studies have considered the impact of gene exp...

    Authors: Bénédicte L. Tremblay, Frédéric Guénard, Benoît Lamarche, Louis Pérusse and Marie-Claude Vohl

    Citation: Genes & Nutrition 2019 14:16

    Content type: Research

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  36. Animals require sufficient intake of a variety of nutrients to support their development, somatic maintenance and reproduction. An adequate diet provides cell building blocks, chemical energy to drive cellular...

    Authors: Aleksandra Zečić, Ineke Dhondt and Bart P. Braeckman

    Citation: Genes & Nutrition 2019 14:15

    Content type: Review

    Published on:

  37. Genetically mediated sensitivity to bitter taste has been associated with food preferences and eating behavior in adults and children. The aim of this study was to assess the association between TAS2R38 bitter...

    Authors: Gabriele Cont, Giulia Paviotti, Marcella Montico, Paola Paganin, Martina Guerra, Antonella Trappan, Sergio Demarini, Paolo Gasparini and Antonietta Robino

    Citation: Genes & Nutrition 2019 14:13

    Content type: Research

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  38. Aging is a complex phenomenon caused by the time-dependent loss of cellular homeodynamics and consequently of physiological organismal functions. This process is affected by both genetic and environmental (e.g...

    Authors: Zoi Evangelakou, Maria Manola, Sentiljana Gumeni and Ioannis P. Trougakos

    Citation: Genes & Nutrition 2019 14:12

    Content type: Review

    Published on:

  39. Olfaction is an important sense influencing food preferences, appetite, and eating behaviors. This hypothesis-driven study aimed to assess associations between olfactory pathway gene methylation signatures, ob...

    Authors: Omar Ramos-Lopez, Jose I. Riezu-Boj, Fermin I. Milagro, M. Angeles Zulet, Jose L. Santos and J. Alfredo Martinez

    Citation: Genes & Nutrition 2019 14:11

    Content type: Research

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  40. Intake of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) reduces fasting triglyceride (TG) levels and may thereby lower cardiovascular disease risk. However, there ar...

    Authors: Amanda Rundblad, Sunniva V. Larsen, Mari C. Myhrstad, Inger Ottestad, Magne Thoresen, Kirsten B. Holven and Stine M. Ulven

    Citation: Genes & Nutrition 2019 14:10

    Content type: Research

    Published on:

  41. Tubers are important crops as well as staple foods in human nutrition. Among tubers, the potato in particular has been investigated for its health effects. However, except for its contribution to energy and ef...

    Authors: Xiaomin Zhou, Qian Gao, Giulia Praticò, Jie Chen and Lars Ove Dragsted

    Citation: Genes & Nutrition 2019 14:9

    Content type: Review

    Published on:

  42. Micro algae’s are worldwide considered as an alternative source of proteins in diets for animals and humans. Micro algae also produce an array of biological active substances with potential to induce beneficia...

    Authors: Marcel Hulst, Rommie van der Weide, Arjan Hoekman and Marinus van Krimpen

    Citation: Genes & Nutrition 2019 14:8

    Content type: Research

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  43. Nuts and vegetable oils are important sources of fat and of a wide variety of micronutrients and phytochemicals. Following their intake, several of their constituents, as well as their derived metabolites, are...

    Authors: Mar Garcia-Aloy, Paul J. M. Hulshof, Sheila Estruel-Amades, Maryse C. J. Osté, Maria Lankinen, Johanna M. Geleijnse, Janette de Goede, Marynka Ulaszewska, Fulvio Mattivi, Stephan J. L. Bakker, Ursula Schwab and Cristina Andres-Lacueva

    Citation: Genes & Nutrition 2019 14:7

    Content type: Review

    Published on:

  44. Hepatic insulin resistance (IR) plays a crucial role in the development of many metabolic diseases, such as type 2 diabetes. MicroRNAs (miRNAs) are involved in the pathogenesis of IR and related diseases; howe...

    Authors: Xue Zhao, Zhao Chen, Zengyuan Zhou, Yuzheng Li, Yuanyuan Wang, Zihao Zhou, Huimin Lu, Changhao Sun and Xia Chu

    Citation: Genes & Nutrition 2019 14:6

    Content type: Research

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  45. The purpose of this study was to draw a global portrait of the current knowledge and interest regarding nutrigenetics in a population of French Canadians from the province of Quebec (Canada).

    Authors: Bastien Vallée Marcotte, Hubert Cormier, Véronique Garneau, Julie Robitaille, Sophie Desroches and Marie-Claude Vohl

    Citation: Genes & Nutrition 2019 14:5

    Content type: Research

    Published on:

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