Research
Obesity is a complex pathology associated with dysbiosis, metabolic alterations, and low-grade chronic inflammation promoted by immune cells, infiltrating and populating the adipose tissue. Probiotic supplemen...
Genes & Nutrition 2017 12:25
Published on: 4 October 2017
Review
Obesity, a major cause of death and disability, is increasing worldwide. Obesity is characterized by a chronic, low-grade inflammatory state which is suggested to play a critical role in the development of obe...
Genes & Nutrition 2017 12:26
Published on: 4 October 2017
Review
Dietary supplementation of essential amino acids (EAAs) has been shown to promote healthspan. EAAs regulate, in fact, glucose and lipid metabolism and energy balance, increase mitochondrial biogenesis, and mai...
Genes & Nutrition 2017 12:27
Published on: 4 October 2017
Research
During evolution, humans colonized different ecological niches and adopted a variety of subsistence strategies that gave rise to diverse selective pressures acting across the genome. Environmentally induced se...
Genes & Nutrition 2017 12:28
Published on: 4 October 2017
Commentary
In the dietary and health research area, biomarkers are extensively used for multiple purposes. These include biomarkers of dietary intake and nutrient status, biomarkers used to measure the biological effects...
Genes & Nutrition 2017 12:24
Published on: 29 September 2017
Review
In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been the object of intensive research. miRNAs have emerged as key mediators of metabolic processes, playing crucial roles in mai...
Genes & Nutrition 2017 12:23
Published on: 25 September 2017
Research
Methionine, a central molecule in one-carbon metabolism, is an essential amino acid required for normal growth and development. Despite its importance to biological systems, methionine is toxic when administer...
Genes & Nutrition 2017 12:22
Published on: 6 September 2017
Research
A key feature of metabolic health is the ability to adapt upon dietary perturbations. Recently, it was shown that metabolic challenge tests in combination with the new generation biomarkers allow the simultane...
Genes & Nutrition 2017 12:21
Published on: 29 August 2017
Research
The ability to digest lactose after weaning, namely, lactase persistence (LP), is encoded by polymorphisms in the MCM6 gene and varies widely in frequency among different human populations. Although, evolution of...
Genes & Nutrition 2017 12:20
Published on: 24 August 2017
Review
The notion of uptake of active diet-derived small RNAs (sRNAs) in recipient organisms could have significant implications for our understanding of oral therapeutics and nutrition, for the safe use of RNA inter...
Genes & Nutrition 2017 12:13
Published on: 7 July 2017
Research
Transgenic expression of small RNAs is a prevalent approach in agrobiotechnology for the global enhancement of plant foods. Meanwhile, emerging studies have, on the one hand, emphasized the potential of transg...
Genes & Nutrition 2017 12:17
Published on: 7 July 2017
Research
A polymorphism in a gene may exert its effects on multiple phenotypes. The aim of this study is to explore the association of 10 metabolic syndrome candidate genes with excess weight and adiposity and evaluate...
Genes & Nutrition 2017 12:19
Published on: 4 July 2017
Discussion
In ancient lore, a bullet cast from silver is the only effective weapon against monsters. The uptake of active diet-derived microRNAs (miRNAs) in consumers may be the silver bullet long sought after in nutriti...
Genes & Nutrition 2017 12:15
Published on: 22 June 2017
Editorial
When a novel nutritional concept comes along, scientists become enthusiastic and start new explorations. In 2012, the field was enthralled with a study suggesting plant-based nucleic acid “information” acts as...
Genes & Nutrition 2017 12:16
Published on: 22 June 2017
Commentary
Extracellular vesicles deliver a variety of cargos to recipient cells, including the delivery of cargos in dietary vesicles from bovine milk to non-bovine species. The rate of discovery in this important line ...
Genes & Nutrition 2017 12:12
Published on: 22 June 2017
Review
It is widely accepted that metabolic disorders, such as obesity, are closely linked to lifestyle and diet. Recently, the central role played by the intestinal microbiota in human metabolism and in progression ...
Genes & Nutrition 2017 12:18
Published on: 15 June 2017
Review
Folic acid and its derivates, known as folates, are chemoprotective micronutrients of great interest because of their essential role in the maintenance of health and genomic integrity. The supplementation of f...
Genes & Nutrition 2017 12:14
Published on: 2 June 2017
Research
Gene expression profiles of intestinal mucosa of chickens and pigs fed over long-term periods (days/weeks) with a diet rich in rye and a diet supplemented with zinc, respectively, or of chickens after a one-da...
Genes & Nutrition 2017 12:11
Published on: 13 April 2017
Research
To elucidate the effects of altered dietary carbohydrate and fat balance on liver and adipose tissue transcriptomes, 3-week-old rats were fed three kinds of diets: low-, moderate-, and high-fat diets (L, M, an...
Genes & Nutrition 2017 12:10
Published on: 8 April 2017
Research
The dietary xanthophylls, lutein and zeaxanthin, accumulate in primate retina and brain, and emerging evidence indicates neural lutein content may be beneficial for cognition. Neural xanthophyll content in pri...
Genes & Nutrition 2017 12:9
Published on: 8 March 2017
Research
High-intensity exercise induces many metabolic responses. In is unknown whether the response in the peripheral blood mononuclear cells (PBMCs) reflects the response in skeletal muscle and whether mRNA expressi...
Genes & Nutrition 2017 12:8
Published on: 3 March 2017
Research
Inflammation plays a central role in chronic diseases occurring in the contemporary society. The health benefits of omega-3 (n-3) fatty acids (FAs), mostly eicosapentaenoic acid (EPA) and docosahexaenoic acid ...
Genes & Nutrition 2017 12:7
Published on: 21 February 2017
Review
Androgens, the main male sex steroids, are the critical factors responsible for the development of the male phenotype during embryogenesis and for the achievement of sexual maturation and puberty. In adulthood...
Genes & Nutrition 2017 12:6
Published on: 16 February 2017
Research
Vitamins and carotenoids are key micronutrients facilitating the maintenance of health, as evidenced by the increased risk of disease with low intake. Optimal phenotypic flexibility, i.e., the ability to respo...
Genes & Nutrition 2017 12:5
Published on: 8 February 2017
Research
The level of omega-6 and omega-3 polyunsaturated fatty acids can affect many cellular systems and function via nuclear receptors or the bioactive lipid regulation of gene expression. The objective of this stud...
Genes & Nutrition 2017 12:4
Published on: 31 January 2017
Genes & Nutrition is affiliated with the European Nutrigenomics Organisation (NuGO). NuGO is an association of universities and research institutes focusing on the joint development of the research area of molecular nutrition, personalized nutrition, nutrigenomics and nutritional systems biology.
