Dietary modulation and structure prediction of rat mucosal pentraxin (Mptx) protein and loss of function in humans

Table 1 Effects of dietary heme on Wistar rats (n = 8)

	Control	Heme
Gain in body weight (g/day)	2.9 ± 0.4	2.8 ± 0.4
Food intake (g/day)	16.2 ± 0.4	16.8 ± 0.3
Fecal output (g wet weight/day)	1.82 ± 0.2	1.73 ± 0.3
Cytotoxicity of fecal water (% lysis)^a	0.9 ± 0.2	46.1 ± 4.7
Relative Mptx expression (Mptx/aldoA)^b	1.0 ± 0.51	0.14 ± 0.10

Values are given mean ± SEM
^aCytotoxicity of 5 μl fecal water was determined against human erythrocytes in a K-release assay [31]
^bThe ratio of Q-PCR measured Mptx and aldolase RNA is indicated. Aldolase A is not modulated by dietary heme [37]. The ratio in the control group was set at 1.0.

ISSN: 1865-3499