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Fig. 1 | Genes & Nutrition

Fig. 1

From: Extracts of Rehmanniae radix, Ginseng radix and Scutellariae radix improve glucose-stimulated insulin secretion and β-cell proliferation through IRS2 induction

Fig. 1

Glucose-stimulated insulin secretion in isolated rat islets. After 16 h incubation in low glucose Dulbecco’s modified Eagles medium (DMEM), isolated mice isles were treated with vehicle [dimethylsulfoxide (DMSO], 50 μg/ml extracts of Galla rhois, Rehmanniae radix, Machilus bark, Ginseng radix, Polygonatum radix or Scutellariae radix, or 2.5 nM exendin-4 (positive control) in low glucose (5 mM) or high glucose (20 mM) Krebs-Ringer buffer for 30 min to measure glucose stimulated insulin secretion. These assays were repeated four times, and the results were expressed as mean ± SD. Asterisks indicate significant differences from the control (DMSO-treated) group in two-sample t-test at P < 0.05

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Genes & Nutrition

ISSN: 1865-3499

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