A mixture of the aqueous extract of Garcinia cambogia, soy peptide and l-carnitine reduces the accumulation of visceral fat mass in rats rendered obese by a high fat diet

Table 1 Body weight gain, visceral fat-pad weight, and serum and hepatic biochemistry of rats fed the high-fat control diet (CD) or the mixture-supplemented diet (CD + M) for 9 weeks. Values are mean ± SEM, n = 10

	CD	CD + M
Body weight gain (g/9 weeks)	463 ± 23.3	385 ± 15.4*
Food efficiency ratio^a	0.27 ± 0.009	0.24 ± 0.007*
Visceral fat-pad weight (g/100 g body weight)
Epididymal	2.86 ± 0.27	2.35 ± 0.10
Perirenal	0.85 ± 0.05	0.57 ± 0.04**
Retroperitoneal	3.33 ± 0.22	2.79 ± 0.05*
Mesenteric	2.29 ± 0.10	1.94 ± 0.03*
Total	9.33 ± 0.58	7.65 ± 0.15*
Serum
Total cholesterol (mmol/l)	4.43 ± 0.58	2.63 ± 0.24*
HDL cholesterol (mmol/l)	1.21 ± 0.09	1.03 ± 0.06
VLDL + LDL cholesterol^b (mmol/l)	2.55 ± 0.32	1.60 ± 0.21*
Triglyceride (mmol/l)	0.37 ± 0.04	0.32 ± 0.04
Free fatty acid (mmol/l)	0.60 ± 0.04	0.35 ± 0.02***
Glucose (mmol/l)	10.4 ± 0.58	8.07 ± 0.44**
Insulin (pmol/l)	641 ± 14.4	178 ± 44.5*
C-peptide (pmol/l)	2,047 ± 226	832 ± 134**
Leptin (ng/ml)	11.0 ± 1.57	6.09 ± 0.84*
Liver
Liver weight (g/100 g of body weight)	5.01 ± 0.18	4.36 ± 0.09**
Cholesterol (μmol/g of liver)	16.4 ± 0.42	14.9 ± 0.32*
Triglyceride (μmol/g of liver)	17.7 ± 0.31	16.6 ± 0.30*

^aBody weight gain for experimental period (g) / food intake for experimental period (g)
^bLDL + VLDL cholesterol = total cholesterol–HDL cholesterol
*P < 0.05; **P < 0.01; ***P < 0.001

ISSN: 1865-3499