Table 1 SNPs related to β-carotene status/metabolism
From: β-Carotene conversion products and their effects on adipose tissue
Gene | Location | rs number | Effect of the minor allele | Reference |
|---|---|---|---|---|
ApoB | C-516T (promoter) | rs934197 | Decreased fasting β-carotene in men | [9] |
BCMO1 | Exon 5 T170 M | n/a | High plasma β-carotene Decreased catalytic activity in vitro | [48] |
BCMO1 | Exon 8 (R267S) or | rs12934922 | Decreased intestinal postprandial β-carotene conversion efficiency, higher fasting β-carotene | [44] |
Exon 6 + exon 8 (R267S + A379 V) | rs7501331 | |||
LIPC | C-480T (promoter) | rs1800588 | Higher β-carotene concentrations in homozygous women | [8] |
LPL | Exon 8 S447X | rs328 | Lower fasting plasma β-carotene | [28] |
SR-BI | Intron 5 | n/a | Decreased fasting β-carotene in men | [9] |