Fig. 1
From: Diet-induced obesity increases NF-κB signaling in reporter mice
In vivo imaging analysis of anesthetized mice harboring a luciferase transgene controlled by NF-κB DNA-binding sites. The figure shows a representative capture of four reporter mice. The heat map is a two-dimensional representation of light emitted ventrally from the mice after luciferin injection. The red squares are examples of regions of interest (ROIs) set during the image analysis to quantify NF-κB activity in different body regions: whole body (ROI 1–4); thorax (ROI 5–8), and abdomen (ROI 9–12)