Fig. 5
From: Diet-induced obesity increases NF-κB signaling in reporter mice
a Body weight change in the NF-κB reporter mice from weeks 1–12, relative to body weight at baseline (week 0; set to 100%) Female (circles) and male (squares) mice were fed either the high-fat diet (HFD; closed symbols) or the low-fat diet (LFD; open symbols). b There was a significant positive correlation between body weight change and thoracic NF-κB activity in both female and male mice in the HFD group. Effect of the high-fat diet (HFD; closed bars) versus the low-fat diet (LFD; open bars) on plasma leptin concentrations (mean ± SEM) in c male and d female NF-κB reporter mice after 0, 5 and 9 weeks of feeding. *P < 0.01