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Table 3 Subject characteristics and postprandial TAG summary measures in the male and female groups and according to age group in the male subjects

From: Introduction to the DISRUPT postprandial database: subjects, studies and methodologies

 

Females

Males

P = (gender)

Men < 50 years

Men ≥ 50 years

P = (age)

Subject characteristics

Age

53.0 ± 10.8

52.2 ± 10.8

NS

41.7 ± 5.4

60.0 ± 6.3

 

Body mass index (kg/m2)

25.2 ± 3.3

26.6 ± 2.4

0.0002

26.3 ± 2.1

26.9 ± 2.6

NS

Blood Pressure (mmHg)

 Systolic

125 ± 16

136 ± 18

<0.0001

130 ± 15

141 ± 19

0.0004

 Diastolic

75 ± 9

84 ± 11

<0.0001

82 ± 10

86 ± 10

0.025

Biochemical data (mmol/L)

 Total cholesterol

5.65 ± 1.04

5.92 ± 1.04

NS

5.69 ± 0.99

6.09 ± 1.05

0.026

 HDL cholesterol

1.63 ± 0.39

1.13 ± 0.29

<0.0001

1.14 ± 0.31

1.12 ± 0.27

NS

 LDL cholesterol

3.50 ± 1.04

3.93 ± 0.96

0.001

3.72 ± 0.90

4.09 ± 0.98

0.026

 Triacylglycerol

1.17 ± 0.41

1.91 ± 0.88

<0.0001

1.92 ± 0.93

1.91 ± 0.85

NS

 Glucose

4.84 ± 0.46

5.30 ± 0.53

<0.0001

5.26 ± 0.53

5.32 ± 0.53

NS

Postprandial TAG data

 AUC (mmol/L × 480 min)

830.0 ± 303.5

1,349.2 ± 589.5

<0.0001

1,356.5 ± 648.6

1,343.8 ± 545.1

NS

 IAUC (mmol/L × 480 min)

232.9 ± 150.0

413.1 ± 239.8

<0.0001

450.3 ± 278.9

385.3 ± 203.1

NS

 MaxC (mmol/L)

2.46 ± 0.87

3.95 ± 1.79

<0.0001

4.05 ± 2.09

3.87 ± 1.53

NS

 TTM (min)

366.7 ± 75.7

392.5 ± 70.8

0.0076

392.3 ± 71.1

392.7 ± 71.0

NS

  1. Values represent mean ± SD
  2. AUC area under the curve, HDL high density lipoprotein, IAUC incremental area under the curve, LDL low density lipoprotein MaxC maximum TAG concentration, NS not significant, TTM time to reach maxC