Fig. 3

Network of proteins, functional classes and cell processes modulated in prostate cancer cells after curcumin treatment. All of these data were extracted from PubMed abstracts using the MedScan Reader software (version 1.1) [25, 80] and then imported to the Pathway Studio software tool (Version 5.0) [78] for visualization. Nodes correspond to proteins (in red), functional classes (in orange). Lines represented the different types of interactions and relationships between the corresponding nodes and curcumin: expression (in black), regulation (in blue). Arrow line represented induction/activation, blunt-ended line represented repression/inactivation