Table 4 Copper deficiency: down-regulated (A) and up-regulated (B) sequences in fatty acids and cholesterol metabolic pathways
Fold induction | ||
|---|---|---|
A | ||
PhlpB | Phospholipase B | −2.01 |
Cd36 | cd36 antigen | −1.50 |
RGD1310224 | Similar to RIKEN CDNA 1810022C23 | −1.43 |
Peci | Peroxisomial delta2-enoyl-CoA-isomerase | −1.42 |
Plcl2_predicted | Phospholipase C-like 2 (predicted) | −1.39 |
Hsd17b4 | Hydroxysteroid (17-beta) dehydrogenase 4 | −1.38 |
Hpgd | 15-Hydroxyprostalandin dehydrogenase | −1.37 |
Cept1 | Choline/ethanolamine phosphotransferase 1 | −1.36 |
Sult1b1 | Sulfotransferase family 1B, member 1 | −1.35 |
Pitpn | Phosphatidylinositol transfer protein | −1.33 |
Ugt2b10_predic. | UDP glycosyltransferase 2 family, polypeptide B10 (predicted) | −1.32 |
Acsl1 | Acyl-CoA synthetase long-chain family member 1 | −1.32 |
Crot | Carnitine O-octanoyltransferase | −1.30 |
Cpt1a | Carnitine-palmitoyltransferase 1, liver | −1.29 |
Insig2 | Insulin induced gene 2 | −1.27 |
Acadvl | Acyl-coenzyme A dehydrogenase, very long chain | −1.25 |
Asah2 | N-Acylsphingosine amidohydrolase 2 | −1.23 |
Aadac | Arylacetamide deacetylase (esterase) | −1.22 |
Cds1 | CDP-diacylglycerol synthase 1 | −1.22 |
Scd2 | Stearoyl-coenzyme A desaturase 2 | −1.22 |
Hadhb | Hydroxyacyl-coenzyme A dehydrogenase/3-ketoacyl-coenzyme A | −1.21 |
Thiolase/enoyl-coenzyme A hydratase (trifunctional protein) | −1.21 | |
Beta subunit | ||
B | ||
Lcat | Lecithin cholesterol acyltransferase | 1.56 |
Pnliprp2 | Pancreatic lipase-related protein 2 | 1.34 |
Pmvk | Phosphomevalonate kinase | 1.24 |
ApoE | Apolipoprotein E | 1.20 |