Fig. 5

A Venn diagram illustrating the number of genes in HepG2 cells that were mutually regulated at 0.4, 0.6 and 1.7 mg/ml of the shoot extracts. The total numbers of genes regulated at 0.4, 0.6 and 1.7 mg/ml of the extracts of A. occidentale were 246, 696 and 4503 respectively. An increase in concentration by 1.5-fold from 0.4 to 0.6 mg/ml was able to increase the number of regulated genes by threefold (65%). Increasing the concentration from 0.4 to 1.7 mg/ml increases the number of regulated genes by 18-fold (95%). A total of 94 genes were mutually regulated in response to the 3 concentrations, 5 were up-regulated and 89 were down-regulated. Ninety-eight genes were mutually regulated in response to the 0.4 and 0.6 mg/ml extracts. On the other hand, 178 were mutually regulated in response to the 0.4 and 1.7 mg/ml extracts. A larger number of genes of 571 were mutually regulated when cells were treated with 0.6 and 1.7 mg/ml extracts