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Fig. 3 | Genes & Nutrition

Fig. 3

From: Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes

Fig. 3

CSE inhibits IL1β-stimulated MMP-13 production in human chondrocytes. Primary chondrocytes (PC) were isolated from 3 donors and cultured and analyzed separately. Serum-starved SW1353 cells and PC were pretreated with 5 μg/ml CSE followed by the coincubation with 10 ng/ml IL1β for 48 h. MMP-13 concentration was determined in the cell culture supernatants using ELISA. Mean values and standard deviations from 2 independent experiments (SW1353) and from 3 donors (PC) are given. *indicates significant differences with respect to cells treated with IL1β only (P < 0.05). #indicates significant differences with respect to untreated controls (P < 0.05)

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Genes & Nutrition

ISSN: 1865-3499

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