Table 1 Genes downregulated by benfotiamine
Symbol | Acc | Description | FC NG | FC HG |
|---|---|---|---|---|
LRRN1 | NM_020873 | Leucine rich repeat neuronal 1 | −3.97 | −3.43 |
RARRES1 | NM_206963 | Retinoic acid receptor responder (tazarotene induced) 1 | −3.62 | −2.50 |
COMP | NM_000095 | Cartilage oligomeric matrix protein | −3.39 | −4.48 |
COL15A1 | NM_001855 | Collagen. type XV, alpha 1 | −3.29 | −3.10 |
SPRR2G | NM_001014291 | Small proline-rich protein 2G | −3.28 | −2.85* |
MDK | NM_001012333 | Midkine (neurite growth-promoting factor 2) | −3.23 | −3.34 |
COL16A1 | NM_001856 | Collagen. type XVI, alpha 1 | −3.18 | −3.05 |
TYMP | NM_001953 | Thymidine phosphorylase | −2.89 | −2.20* |
PACSIN1 | NM_020804 | Protein kinase C and casein kinase substrate in neurons 1 | −2.89 | −2.30 |
MYOT | NM_006790 | Myotilin | −2.86 | −2.40* |
FAM180B | XM_001716425 | Family with sequence similarity 180, member B | −2.81 | −3.25 |
FRAS1 | NM_025074 | Fraser syndrome 1 | −2.75 | −2.88 |
MGC16121 | XM_001128419 | Hypothetical protein MGC16121 | −2.68 | −1.45* |
MXRA5 | NM_015419 | Matrix-remodeling associated 5 | −2.67 | −2.72 |
SORBS2 | NM_021069 | Sorbin and SH3 domain containing 2 | −2.66 | −2.96 |
HES4 | NM_021170 | Hairy and enhancer of split 4 (Drosophila) | −2.57 | −2.43 |
NOX4 | NM_016931 | NADPH oxidase 4 | −2.56 | −3.07 |
CTHRC1 | NM_138455 | Collagen triple helix repeat containing 1 | −2.54 | −1.90 |
CHN2 | NM_004067 | Chimerin (chimaerin) 2 | −2.53 | −1.95* |
CIRBP | NM_001280 | Cold-inducible RNA-binding protein | −2.51 | −1.94* |