Fig. 4From: Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory networkJAK/STAT signaling pathway targeted by different inhibitors. These inhibitors target the following points in the JAK/STAT signaling pathway: constitutive activation of JAK2, STAT3 phosphorylation, formation of the STAT dimer and binding activity of STAT3 to DNA. In contrast, the phosphatase SHP-1 can be activatedBack to article page