Fig. 1
From: Histone deacetylase modulators provided by Mother Nature
Acetylation/deacetylation of lysine residues. The reaction of acetylation on the ε-nitrogen of lysine residues is catalyzed by enzymes within the histone acetyl transferase (HAT) family, using acetyl-coenzyme A (acetyl-CoA) as donor of acetyl moiety. This is a reversible reaction catalyzed by enzymes within the histone deacetylase (HDAC) family