Epidemiological profiles between equol producers and nonproducers: a genomewide association study of the equol-producing phenotype

Table 3 General linear model analysis of the main effects of the equol producer phenotype and rs6927608 and the effects of their interaction

	General linear model analysis p values^a			General linear model analysis p values^b
	Equol	rs6927608	Equol × rs6927608	Equol	rs6927608	Equol × rs6927608
Anthropometric indexes
Pulse rate (n/min)	0.057	0.396	0.192	0.053	0.421	0.176
Systolic blood pressure (mm Hg)	0.115	0.718	1.3 × 10 ⁻⁴	0.134	0.708	1.3 × 10 ⁻⁴
Diastolic blood pressure (mm Hg)	0.515	0.766	0.046	0.606	0.774	0.041
Height (cm)	0.176	0.595	0.622	0.173	0.602	0.662
Body mass index (kg/m²)	0.756	0.659	0.832	0.640	0.591	0.832
Blood biochemistry index
Fasting glucose (μg/dl)	0.105	0.729	0.203	0.119	0.692	0.243
Fasting insulin (μg/dl)	0.682	0.829	0.765	0.685	0.825	0.752
Total cholesterol (μg/dl)	0.605	0.063	0.240	0.666	0.077	0.346
High-density lipoprotein cholesterol (μg/dl)	0.490	0.095	0.638	0.580	0.101	0.780
Triglycerides (μg/dl)	0.730	0.545	0.430	0.732	0.505	0.391

Statistically significant associations (p value <0.05) are shown underlined in bold
^aGeneral linear model analysis, controlling for area, age, and sex
^bGeneral linear model analysis, controlling for area, age, sex, alcohol drinking and smoking

ISSN: 1865-3499