| Experimental group | ||||||
---|---|---|---|---|---|---|---|
Dams1 | Dams2 | Male pups | |||||
CuD | CuA | CuD | CuA | FeD | CuD | CuA | |
Liver levels | |||||||
GPI-Cp | 0.65 ± 0.06* | 1.00 ± 0.03 | 0.64 ± 0.05c | 1.00 ± 0.14b | 1.52 ± 0.10a | 0.40 ± 0.24* | 1.00 ± 0.10 |
TfR1 | 0.71 ± 0.22 | 1.00 ± 0.14 | 0.75 ± 0.13b | 1.00 ± 0.10b | 4.85 ± 0.18a | 0.55 ± 0.02* | 1.00 ± 0.05 |
TfR2 | 0.80 ± 0.04* | 1.00 ± 0.09 | 0.66 ± 0.09b | 1.00 ± 0.11a | 0.45 ± 0.07b | 0.30 ± 0.05* | 1.00 ± 0.12 |
Fpn | 1.06 ± 0.07 | 1.00 ± 0.15 | 1.14 ± 0.18a | 1.00 ± 0.24a | 0.58 ± 0.05a | 1.74 ± 0.18* | 1.00 ± 0.12 |
Spleen levels | |||||||
GPI-Cp | 0.23 ± 0.01* | 1.00 ± 0.06 | 0.12 ± 0.03c | 1.00 ± 0.04a | 0.78 ± 0.07b | 0.51 ± 0.01* | 1.00 ± 0.09 |
TfR1 | 6.40 ± 0.71* | 1.00 ± 0.23 | 1.44 ± 0.49b | 1.00 ± 0.16b | 4.04 ± 0.22a | 1.94 ± 0.06* | 1.00 ± 0.09 |
Fpn | 0.76 ± 0.15 | 1.00 ± 0.10 | 0.70 ± 0.05b | 1.00 ± 0.13b | 1.54 ± 0.16a | 1.09 ± 0.11 | 1.00 ± 0.09 |
CCS | 7.35 ± 0.65* | 1.00 ± 0.32 | 2.61 ± 0.14a | 1.00 ± 0.07b | 1.41 ± 0.14b | 2.88 ± 0.37* | 1.00 ± 0.06 |
NHI, μg/g | 462 ± 80.7* | 656 ± 33.5 | 204 ± 39.3b | 497 ± 102a | 59.8 ± 3.89b | 25.0 ± 4.6* | 36.2 ± 1.1 |