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Fig. 6 | Genes & Nutrition

Fig. 6

From: Growth factor TGF-β induces intestinal epithelial cell (IEC-6) differentiation: miR-146b as a regulatory component in the negative feedback loop

Fig. 6

Activation of the ERK1/2 pathway is involved in TGF-β-induced miR-146b up-regulation during IEC-6 cell differentiation. a IEC-6 cells were treated with 50 ng/ml TGF-β for the indicated times, and cells were analyzed for ERK1/2 and p-ERK1/2 by immunoblotting. b, c IEC-6 cells were pre-treated with 10 μM U0126 for 15 min before treatment with 50 ng/ml TGF-β for 6 h. U0126 inhibition of p-ERK1/2 was confirmed by immunoblotting (b) and miR-146b expression was observed by real-time Q-PCR (c)

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Genes & Nutrition

ISSN: 1865-3499

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