Table 6 Effect of transsulphuration pathway–related dietary, biochemical and genetic variables on diastolic and systolic blood pressure: p has been determined using a stepwise regression model that takes account of Hcy, Cys, GSH, dietary natural and synthetic folate, dietary vitamin B₆ and B₁₂, and CTH-G1364T and CBS-844ins68 genotypes. Values provided are p (r ² for whole model and slope estimate)

Homocysteine

NS

NS

Cysteine

<0.0001 (r ² = 0.1368, −0.0745)

0.0107 (r ² = 0.0508, −0.0680)

Glutathione

NS

NS

Dietary natural folate

0.0567 (r ² = 0.1368, 0. 0098)

NS

Dietary synthetic folate

0.0548 (r ² = 0.1368, 0. 0081)

NS

Dietary vitamin B₁₂

0.0095 (r ² = 0.1368, −0.0687)

NS

Dietary vitamin B₆

NS

NS

CTH-G1364T

NS

NS

CBS-844ins68

0.0267 (r ² = 0.1368, 6.1198)

0.0228 (r ² = 0.0508, 10.4235)