Table 4 Changes in the expression of genes in PBMCs involved in glycerophospholipid metabolism after n-3 PUFA supplementation in responders and non-responders (P = 0.02 and P = 0.02, respectively)
Gene symbol | Gene name | Responders (n = 6) | Non-responders (n = 6) |
|---|---|---|---|
AGPAT3 | 1-Acylglycerol-3-phosphate O-acyltransferase 3 | 1.223 | Â |
AGPAT4 | 1-Acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) | −1.238 |  |
CDIPT | CDP-diacylglycerol–inositol 3-phosphatidyltransferase |  | 1.257 |
CHAT | Choline O-acetyltransferase | −1.273 |  |
CHKA | Choline kinase alpha | −1.306 |  |
CHKB | Choline kinase beta |  | −1.565 |
DGKE | Diacylglycerol kinase, epsilon 64 kDa |  | −1.454 |
DGKZ | Diacylglycerol kinase, zeta |  | −1.256 |
ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2 | 1.247 | −1.418 |
ETNK1 | Ethanolamine kinase 1 | −1.214 | −1.343 |
GPAM | Glycerol-3-phosphate acyltransferase, mitochondrial | −1.422 | 1.502 |
MGLL | Monoglyceride lipase | 1.547 | −1.290 |
NAPEPLD | N-Acyl phosphatidylethanolamine phospholipase D | −1.357 | −1.382 |
PEMT | Phosphatidylethanolamine N-methyltransferase | 1.338 | Â |
PHKA1 | Phosphorylase kinase, alpha 1 (muscle) | 1.222 | −1.204 |
PIGF | Phosphatidylinositol glycan anchor biosynthesis, class F | Â | 1.229 |
PIGO | Phosphatidylinositol glycan anchor biosynthesis, class O | 1.279 | Â |
PLA2G6 | Phospholipase A2, group VI (cytosolic, calcium-independent) | 1.378 | Â |
PLA2G2A | Phospholipase A2, group IIA (platelets, synovial fluid) | −1.203 |  |
PLA2G2C | Phospholipase A2, group IIC | Â | 1.396 |
PLA2G2D | Phospholipase A2, group IID | Â | 1.232 |
PLA2G2F | Phospholipase A2, group IIF | 1.294 | Â |
PLA2G4A | Phospholipase A2, group IVA (cytosolic, calcium-dependent) |  | −1.250 |
PLCB1 | Phospholipase C, beta 1 (phosphoinositide-specific) | Â | 1.246 |
PLCD3 | Phospholipase C, delta 3 | Â | 1.340 |
PLCL1 | Phospholipase C-like 1 | −1.504 | 1.450 |
PPAP2A | Phosphatidic acid phosphatase type 2A | 1.336 | 1.207 |
PPAP2B | Phosphatidic acid phosphatase type 2B | Â | 1.283 |
PPAP2C | Phosphatidic acid phosphatase type 2C | 1.251 | −1.462 |
PPAPDC1A | Phosphatidic acid phosphatase type 2 domain containing 1A | −1.276 |  |