Table 7 Changes in the expression of genes in PBMCs involved in linoleic acid metabolism after n-3 PUFA supplementation in responders and non-responders (P = NS and P = 0.08, respectively)
Gene symbol | Gene name | Responders (n = 6) | Non-responders (n = 6) |
|---|---|---|---|
ALOX5 | Arachidonate 5-lipoxygenase |  | −1.229 |
ALOX15B | Arachidonate 15-lipoxygenase, type B | Â | 1.302 |
CYP2F1 | Cytochrome P450, family 2, subfamily F, polypeptide 1 |  | −1.214 |
CYP2J2 | Cytochrome P450, family 2, subfamily J, polypeptide 2 | Â | 1.235 |
CYP4F8 | Cytochrome P450, family 4, subfamily F, polypeptide 8 |  | −1.326 |
FADS2 | Fatty acid desaturase 2 |  | −1.306 |
LCAT | Lecithin-cholesterol acyltransferase | Â | 1.225 |
PLA2G2C | Phospholipase A2, group IIC | Â | 1.396 |
PLA2G2D | Phospholipase A2, group IID | Â | 1.232 |
PLA2G4A | Phospholipase A2, group IVA (cytosolic, calcium-dependent) |  | −1.250 |