Table 4 Obesity polymorphisms associated with adiposity after δ15N adjustment
Gene | SNP | BMI | PBF | HC | ThC | WC |
|---|---|---|---|---|---|---|
NEGR1 | rs2815752 | 0.222 | 0.056 | 0.109 | 0.055 | 0.081 |
(β = −0.3, SE = 0.2) | (β = −0.4, SE = 0.2) | (β = −0.4, SE = 0.2) | (β = −0.6, SE = 0.3) | (β = −0.5, SE = 0.3) | ||
TMEM18 | rs7561317 | 0.048 | 0.073 | 0.103 | 0.202 | 0.034 |
(β = 0.5, SE = 0.2) | (β = 0.4, SE = 0.2) | (β = 0.4, SE = 0.2) | (β = 0.4, SE = 0.3) | (β = 0.6, SE = 0.3) | ||
ETV5 | rs7647305 | 0.006 | 0.006 | 0.002 | 0.003 | 0.009 |
(β = −1.5, SE = 0.6) | (β = −1.4, SE = 0.5) | (β = −1.8, SE = 0.6) | (β = −2.0, SE = 0.7) | (β = −1.9, SE = 0.7) | ||
GNPDA2 | rs10938397 | 0.821 | 0.761 | 0.315 | 0.267 | 0.867 |
(β = 0.1, SE = 0.2) | (β = 0.1, SE = 0.2) | (β = 0.2, SE = 0.2) | (β = 0.3, SE = 0.3) | (β = 0.1, SE = 0.3) | ||
BDNF | rs6265 | 0.531 | 0.646 | 0.943 | 0.859 | 0.396 |
(β = 0.4, SE = 0.6) | (β = 0.2, SE = 0.5) | (β = 0.0, SE = 0.6) | (β = 0.1, SE = 0.7) | (β = 0.6, SE = 0.7) | ||
MTCH2 | rs10838738 | 0.682 | 0.550 | 0.556 | 0.440 | 0.797 |
(β = 0.1 SE = 0.2) | (β = 0.1, SE = 0.2) | (β = 0.1, SE = 0.2) | (β = 0.2, SE = 0.2) | (β = 0.1, SE = 0.2) | ||
SH2B1 | rs7498665 | 0.111 | 0.136 | 0.239 | 0.092 | 0.179 |
(β = 0.3, SE = 0.2) | (β = 0.2, SE = 0.2) | (β = 0.2, SE = 0.2) | (β = 0.4, SE = 0.2) | (β = 0.3, SE = 0.2) | ||
FTO | rs9939609 | 0.010 | 0.004 | 0.008 | 0.010 | 0.020 |
(β = 0.6, SE = 0.2) | (β = 0.6, SE = 0.2) | (β = 0.6, SE = 0.2) | (β = 0.7, SE = 0.3) | (β = 0.7, SE = 0.3) | ||
MC4R | rs17782313 | 0.377 | 0.726 | 0.243 | 0.094 | 0.328 |
(β = 0.3, SE = 0.3) | (β = 0.1, SE = 0.3) | (β = 0.4, SE = 0.3) | (β = 0.6, SE = 0.4) | (β = 0.4, SE = 0.4) | ||
KCTD15 | rs29941 | 0.301 | 0.192 | 0.319 | 0.177 | 0.405 |
(β = 0.2, SE = 0.2) | (β = 0.2, SE = 0.2) | (β = 0.2, SE = 0.2) | (β = 0.3, SE = 0.2) | (β = 0.2, SE = 0.3) |