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Table 6 Variation (%) in adiposity phenotypes explained by GRS association and GRS interactions with n-3 PUFA intake

From: Obesity polymorphisms identified in genome-wide association studies interact with n-3 polyunsaturated fatty acid intake and modify the genetic association with adiposity phenotypes in Yup’ik people

Variable

BMI

PBF

HC

ThC

WC

GRS

0.7

0.3

0.5

0.7

0.5

GRS*δ15N

1.7

0.8

1.4

1.5

1.4

  1. Results significant at p ≤ 0.05 are highlighted in bold. Variation attributed to GRS after adjustment for age, sex, community group, and n-3 PUFA intake. Variation attributed to GRS*n-3 PUFA interaction after adjustment for age, sex, community group, and n-3 PUFA intake
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Genes & Nutrition

ISSN: 1865-3499

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