The nutrigenomic investigation of C57BL/6N mice fed a short-term high-fat diet highlights early changes in clock genes expression

Table 5 Top 10 of the differentially expressed genes in the cecum of mice at T2, in response to high-fat diet

Gene symbol^a	Accession number	Definition	logFC^b	q value
Bmal1	NM_007489.3	Mus musculus aryl hydrocarbon receptor nuclear translocator–like (Arntl) or brain muscle Arnt-like-1 (Bmal1), mRNA	−1.17	0.00032
Tef	NM_153484.2	Mus musculus thyrotroph embryonic factor (Tef), transcript, mRNA	+1.96	0.00241
Fst	NM_008046.2	Mus musculus follistatin (Fst), mRNA	−0.82	0.00430
Nr1d2	NM_011584.3	Mus musculus nuclear receptor subfamily 1, group D, member 2 (Nr1d2), mRNA	+1.41	0.01701
H2-Q10	NM_010391.4	Mus musculus histocompatibility 2, Q region locus 10 (H2-Q10), mRNA	−1.11	0.01719
Tspan4	NM_053082.2	Mus musculus tetraspanin 4 (Tspan4), mRNA	+0.66	0.02231
Hlf	NM_172563.3	Mus musculus hepatic leukemia factor (Hlf), mRNA	+0.85	0.03847
Kif26b	NM_177757.3	Mus musculus kinesin family member 26B (Kif26b), mRNA	−0.57	0.16457
Slc30a10	NM_001033286.2	Mus musculus solute carrier family 30, member 10 (Slc30a10), mRNA	−1.12	0.18149
Nfil3	NM_017373.3	Mus musculus nuclear factor, interleukin 3, regulated (Nfil3), mRNA	−0.52	0.18149

Genes differentially expressed with a q value ≤0.2 in the cecum of HF mice (n = 6) compared with CTR mice (n = 6)
^aGenes are sorted based on q value
^bThe fold change is expressed in log2

ISSN: 1865-3499