Association of genetic variants of ghrelin, leptin and UCP2 with malnutrition inflammation syndrome and survival in end-stage renal disease patients

Table 3 Combined analysis of various groups

Group	Patient	Control	OR (95 % CI)	P value
Group 1^a	107 (41.6)	102 (51.0)	Reference
Group 2^b	150 (58.3)	98 (49.0)	1.5 (1.1–2.1)	0.04*

Group	Normal	Malnourished	OR (95 % CI)	P value
Group 1^a	42 (53.8)	65 (36.3)	Reference
Group 2^b	36 (46.1)	114 (63.7)	2.0 (1.2–3.5)	0.01*

Group	Inflamed	Non-inflamed	OR (95 % CI)	P value
Group 1^a	46 (45.5)	61 (39.1)	Reference
Group 2^b	55 (54.5)	95 (60.9)	1.3 (0.7–2.1)	0.3

Group	Period < 1 year	Period ≥ 1 year	OR (95 % CI)	P value
Group 1^a	69 (40.5)	38 (43.6)	Reference
Group 2^b	101 (59.5)	49 (56.4)	1.1 (0.6–1.9)	0.68

Period is categories of period of dialysis in patients. Logistic regression analysis was used to compare groups
* P ≤ 0.05 significant, values in parenthesis are percent frequencies
^aGroup 1 = 0–2 alleles of low producer of ghrelin and leptin and high energy expenditure of UCP2 (I)
^bGroup 2 = 3–4 alleles of low producer of ghrelin and leptin and high energy expenditure of UCP2 (I)

ISSN: 1865-3499