Table 2 Genotype distributions and allele frequencies of PCMT1 rs4816 and rs4552 in NTD and control groups
Polymorphism | Genotype | NTDs n (%) | Control n (%) | OR (95 % CI) | P a |
|---|---|---|---|---|---|
rs4816: A > G (Ile120Val) | 116 | 141 | |||
AA | 70 (60.3) | 87 (61.7) | 1 | ||
AG | 37 (31.9) | 45 (31.9) | 1.02 (0.597, 1.748) | 0.937 | |
GG | 9 (7.8) | 9 (6.4) | 1.24 (0.468, 3.299) | 0.191 | |
rs4552: T > A | 120 | 144 | |||
TT | 75 (62.5) | 91 (63.2) | 1 | ||
AT | 42 (35.0) | 48 (33.3) | 1.06 (0.635, 1.776) | 0.820 | |
AA | 3 (2.5) | 5 (3.5) | 0.73 (0.168, 3.146) | 0.670 |