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Table 3 Distribution of rs4816 and association with NTD subtypes

From: PCMT1 gene polymorphisms, maternal folate metabolism, and neural tube defects: a case–control study in a population with relatively low folate intake

Genotypes

Control (n = 141), n (%)

Anencephaly (n = 50), n (%)

Spina bifida (n = 55), n (%)

Encephalocele (n = 11), n (%)

AA

87 (61.7)

29 (58.0)

36 (65.5)

5 (45.5)

AG/GG

54 (38.3)

21 (42.0)

19 (34.5)

6 (54.5)

OR (95 % CI)

 

1.17 (0.61, 2.25)

0.85 (0.44, 1.63)

1.93 (0.56, 6.64)

P a

 

0.645

0.625

0.288

  1. aχ2 test was used to calculate P values
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Genes & Nutrition

ISSN: 1865-3499

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